Tetrakis(triphenylphosphine)palladium(0)
- CAS No.14221-01-3
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity Pd(0) catalyst designed for efficient cross-coupling reactions. Ideal for Suzuki, Heck, and Stille reactions in pharmaceutical manufacturing and fine chemical synthesis.
Request a Quote & Full COAProduct Technical Details
Product Overview
Tetrakis(triphenylphosphine)palladium(0), commonly abbreviated as Pd(PPh3)4, stands as a cornerstone reagent in modern organometallic chemistry and industrial organic synthesis. This zero-valent palladium complex is renowned for its exceptional catalytic activity in facilitating carbon-carbon bond formation. Our manufacturing process ensures high stability and reproducibility, making it a preferred choice for research laboratories and large-scale pharmaceutical production facilities worldwide.
The compound features a central palladium atom coordinated with four triphenylphosphine ligands. This specific configuration provides the necessary electron richness and steric environment to promote oxidative addition and reductive elimination cycles efficiently. As a leading global manufacturer, we prioritize strict quality control measures to guarantee consistent performance across every batch.
Technical Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 14221-01-3 |
| Molecular Formula | C72H60P4Pd |
| Molecular Weight | 1155.56 g/mol |
| Purity | >95% |
| Appearance | Yellow crystalline powder |
| Melting Point | 103-107 °C |
| Storage Temperature | 2-8 °C |
| Solubility | Insoluble in water, soluble in organic solvents |
Industrial Applications
This versatile catalyst is extensively utilized in the synthesis of complex organic molecules, particularly within the pharmaceutical and agrochemical sectors. It serves as a critical component in various named reactions that construct biaryl structures and conjugated systems. Key applications include the Suzuki-Miyaura coupling, which connects boronic acids with halides, and the Heck reaction for olefin arylation. Additionally, it is effective in Stille couplings, Sonogashira reactions for alkyne synthesis, and carbonylation processes.
Beyond pharmaceutical intermediates, this palladium complex supports material science advancements, including the development of organic light-emitting diodes (OLEDs) and conductive polymers. Its ability to operate under relatively mild conditions makes it suitable for sensitive substrates that might degrade under harsher catalytic systems. Manufacturers rely on this reagent to optimize yield and reduce reaction times in multi-step synthesis routes.
Storage and Handling
Due to its sensitivity to air and light, proper handling protocols are essential to maintain catalytic activity. The product should be stored under an inert atmosphere, such as nitrogen or argon, at refrigerated temperatures between 2 to 8 degrees Celsius. Exposure to ambient air can lead to oxidation of the palladium center, diminishing its effectiveness. We recommend using glovebox techniques or Schlenk lines during transfer and weighing operations.
Safety data sheets indicate that while stable under normal conditions, standard laboratory personal protective equipment should be worn. Avoid inhalation of dust and contact with skin or eyes. In case of spills, collect using inert absorbent materials and dispose of according to local hazardous waste regulations. Our packaging is designed to minimize air exposure during transit, ensuring the product arrives in optimal condition for immediate use.
Quality Assurance and Supply
We commit to delivering premium-grade chemicals supported by comprehensive documentation. Each shipment includes a Certificate of Analysis (COA) detailing purity levels, residual solvent content, and heavy metal analysis. Our supply chain is robust, capable of fulfilling bulk orders for industrial clients while maintaining the flexibility to serve research institutions requiring smaller quantities. Contact our technical sales team for customized synthesis routes, pricing tiers, and logistical support tailored to your specific production needs.
