Speciality Chemicals

Trifluoroacetic Acid Pentafluorophenyl Ester

  • CAS No.14533-84-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity condensation reagent for peptide coupling and organic synthesis. Available in bulk with COA.

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Product Technical Details

Product Overview

Trifluoroacetic Acid Pentafluorophenyl Ester is a highly specialized chemical reagent designed for advanced organic synthesis and peptide coupling applications. As a premier manufacturer, we supply this critical intermediate with exceptional purity standards to support research and industrial production needs. This compound serves as an activated ester, facilitating efficient amide bond formation while minimizing unwanted side reactions such as racemization. Its unique chemical structure makes it an indispensable tool for chemists working on complex molecular architectures.

Key Chemical Properties

This reagent is characterized by its high reactivity and stability under standard laboratory conditions. The pentafluorophenyl group acts as an excellent leaving group, enhancing the electrophilicity of the carbonyl carbon. This property ensures rapid reaction kinetics during coupling processes. The material is supplied as a colorless transparent liquid, indicating high levels of refinement and absence of colored impurities. Rigorous quality control measures are implemented throughout the manufacturing process to guarantee consistency across batches.

Industrial Applications

The primary application of this ester lies in peptide synthesis, where it activates carboxylic acids for coupling with amines. It is particularly valued in the production of pharmaceutical intermediates and bioactive compounds. Beyond peptides, it is utilized in various organic synthesis routes requiring efficient condensation reactions. The reagent supports the development of new materials and fine chemicals where precision and yield are paramount. Its versatility allows it to function effectively in diverse solvent systems commonly used in modern chemical laboratories.

Quality Specifications

ParameterSpecification
CAS Number14533-84-7
Molecular FormulaC8F8O2
Molecular Weight280.07 g/mol
Purity (GC)≥98.0%
AppearanceColorless transparent liquid
Boiling Point122-123°C
Density1.63 g/cm³
Refractive Index1.368

Safety and Storage

Proper handling procedures must be followed to ensure safety during use. This chemical is classified under Hazard Class 3 and should be stored in a cool, ventilated area away from incompatible substances. We recommend using appropriate personal protective equipment when handling this reagent. Packaging is available in 200 kg drums or customized according to specific client requirements. Our logistics network ensures secure global shipping with full compliance to international transport regulations including UN3272 standards. Each shipment is accompanied by a Certificate of Analysis to verify product quality and specifications.