Speciality Chemicals

Triisopropylsilyl trifluoromethanesulfonate

  • CAS No.80522-42-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity Triisopropylsilyl trifluoromethanesulfonate reagent for advanced organic synthesis and pharmaceutical R&D applications.

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Product Technical Details

Product Overview

Triisopropylsilyl trifluoromethanesulfonate, commonly known as TIPS-OTf, is a highly reactive silylating agent utilized extensively in modern organic synthesis and pharmaceutical research. This fluorinated reagent serves as a critical tool for introducing the triisopropylsilyl (TIPS) protecting group onto hydroxyl functions within complex molecular structures. Due to the exceptional leaving group ability of the trifluoromethanesulfonate moiety, this compound offers superior reaction kinetics compared to traditional chlorosilanes. Our manufacturing process ensures consistent quality suitable for demanding laboratory and industrial scale applications.

Technical Specifications

We adhere to strict quality control protocols to guarantee the performance and reliability of every batch. The following table outlines the key physical and chemical properties verified through our analytical laboratories.

ParameterSpecification
CAS Number80522-42-5
Molecular FormulaC10H21F3O3SSi
Molecular Weight306.42 g/mol
AppearanceTransparent light brown to orange-brown liquid
Density1.14 g/mL at 25 °C
Boiling Point45-46 °C at 0.03 mm Hg
Refractive Indexn20/D 1.415
Flash Point213 °F

Industrial Applications

This specialty chemical finds widespread utility across multiple high-tech sectors. In pharmaceutical development, it is employed to protect sensitive functional groups during multi-step synthesis routes, ensuring high yields and selectivity. The steric bulk of the triisopropylsilyl group provides robust stability against various reaction conditions, making it ideal for complex molecule construction. Additionally, it is utilized in the development of new materials and agrochemicals where precise fluorination and silylation are required. Our fluorochemical platform supports customers in scaling from initial research to commercial production.

Quality And Safety

Shanghai Fluorine Technology is committed to providing a complete industrial chain solution for fluorine-containing products. We maintain rigorous standards for storage and transportation to preserve product integrity. Each shipment is accompanied by a Certificate of Analysis (COA) to verify purity and specifications. Safety data sheets are provided to ensure proper handling procedures are followed in your facility. We invite global partners to contact us for bulk pricing and technical support regarding synthesis routes and manufacturing processes.