Speciality Chemicals

(Triphenylphosphonio)difluoroacetate

  • CAS No.1449521-05-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity (Triphenylphosphonio)difluoroacetate is a specialized fluorinating reagent designed for precise difluoromethylene incorporation in organic synthesis and pharmaceutical R&D.

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Product Technical Details

Product Overview

(Triphenylphosphonio)difluoroacetate, frequently referred to as PDFA, represents a significant advancement in modern organofluorine chemistry. This specialized reagent serves as a stable and reliable source of difluoromethylene units, enabling chemists to introduce fluorine atoms into complex molecular architectures with exceptional precision. As a solid phosphonium salt, it offers superior handling safety and storage stability compared to traditional gaseous fluorinating agents, making it an ideal choice for both laboratory-scale research and large-scale industrial manufacturing processes. Our company provides this compound with stringent quality controls to ensure consistent performance in sensitive synthetic routes.

Chemical Properties and Reactivity

The molecular structure of 2,2-difluoro-2-triphenylphosphaniumyl acetate facilitates unique reactivity patterns essential for contemporary medicinal chemistry and materials science. Researchers utilize this building block to enhance the metabolic stability and bioavailability of pharmaceutical candidates by strategically placing fluorine atoms. The difluoromethylene group is increasingly recognized for its ability to mimic natural functional groups while resisting enzymatic degradation, thereby extending the half-life of drug molecules. Consequently, this reagent plays a pivotal role in the development of novel therapeutic agents and advanced agrochemical formulations. Its compatibility with various reaction conditions allows for versatile application across multiple synthetic methodologies, including nucleophilic substitutions and coupling reactions.

Industrial Applications

Applications extend beyond pharmaceuticals into the realm of new materials science and crop protection. The incorporation of fluorine atoms often imparts desirable properties such as thermal stability, chemical resistance, and altered electronic characteristics to polymers and fine chemicals. Our fluorinating reagents support the creation of high-performance materials used in electronics, coatings, and specialized industrial applications. Furthermore, the compound serves as a critical intermediate in the synthesis of specialized pesticides, contributing to global food security through improved crop protection solutions. We support clients in scaling these applications from early-stage discovery to commercial production with reliable supply chains.

Quality Assurance and Specifications

Shanghai Fluorine Technology is committed to establishing a complete fluorochemical products and technology platform. We provide customers with convenient one-stop services ranging from raw material procurement to rigorous quality control. Our facility adheres to international standards, ensuring every batch of (Carboxydifluoromethyl)triphenylphosphonium inner salt meets specified purity levels. We offer comprehensive documentation including Certificates of Analysis (COA) and safety data sheets. Our logistics network ensures timely global delivery, supporting R&D teams and manufacturing plants worldwide. Partner with us for reliable supply chains and technical expertise in fluorine chemistry.

  • High purity suitable for sensitive synthetic transformations
  • Stable solid form for safer handling and storage
  • Versatile applications in pharma and agrochemicals
  • Supported by comprehensive technical documentation
  • Global shipping with secure packaging
ParameterValue
Product Name(Triphenylphosphonio)difluoroacetate
CAS Number1449521-05-4
Molecular FormulaC20H15F2O2P
Molecular Weight356.30
AppearanceWhite to off-white powder
Purity98% min