Melanotan I, chemically known as Afamelanotide and identified by CAS number 75921-69-6, is a synthetic peptide that has garnered significant attention in scientific and medical research. As an analogue of the naturally occurring hormone alpha-melanocyte-stimulating hormone (α-MSH), its primary function is to influence the body's melanin production pathway. This makes it a subject of great interest for conditions related to skin pigmentation and light sensitivity.

The core of Melanotan I's activity lies in its interaction with the melanocortin 1 receptor (MC1R), predominantly found on melanocytes. When Afamelanotide binds to MC1R, it initiates a signaling cascade that stimulates melanogenesis, the process by which melanin is synthesized. Melanin is crucial for skin health as it absorbs UV radiation, offering a degree of natural photoprotection. This property is particularly beneficial for individuals with conditions like Erythropoietic Protoporphyria (EPP), where impaired melanin production leads to severe photosensitivity. Research into afamelanotide for erythropoeitic protoporphyria shows promising results in improving patients' ability to tolerate sunlight.

The formulation of Melanotan I is typically as a lyophilized powder, which ensures stability and ease of reconstitution for research purposes. Understanding what is afamelanotide mt-1 is fundamental to grasping its potential. Studies aim to elucidate the precise mechanisms through which it enhances melanin production and provides photoprotective effects, contributing to the growing field of peptide therapeutics.

Beyond EPP, the photoprotective properties of synthetic peptide afamelanotide are being explored for broader applications. This includes research into its potential to reduce sun damage, accelerate tanning, and even treat certain light-induced skin conditions. The availability of this compound for research, often marketed as afamelanotide mt-1 lyophilized powder, supports ongoing scientific inquiry. NINGBO INNO PHARMCHEM CO.,LTD. plays a role in providing researchers with access to such advanced compounds, fostering further investigation into their therapeutic potential.

The scientific community's interest in afamelanotide cas 75921-69-6 underscores its importance in the study of melanogenesis and photoprotection. As research progresses, the understanding of how does afamelanotide work continues to deepen, potentially leading to new treatment strategies for various skin disorders and light-related sensitivities.