In the realm of synthetic organic chemistry, the strategic use of well-defined intermediates is fundamental to creating complex molecules efficiently. 1,3-Dimethyl-5-iodobenzene, identified by its CAS number 22445-41-6, stands out as a valuable building block due to its specific structural features and reactivity.

Chemical Characteristics of 1,3-Dimethyl-5-iodobenzene

This compound, also known by its synonym 1-Iodo-3,5-dimethylbenzene, is characterized as an organic synthesis intermediate. Its physical presentation is typically a pink-brown to red transparent liquid. A key specification is its purity, with an assay of ≥98.0%. Other important physical and chemical properties include a density of 1.6±0.1 g/cm³, a boiling point of 229.9±9.0 °C at 760 mmHg, and an index of refraction of 1.593. These parameters are crucial for its effective application in various chemical processes.

The Power of the Iodine Substituent

The iodine atom within 1,3-dimethyl-5-iodobenzene is the primary source of its synthetic utility. As an aryl iodide, it is highly reactive in palladium-catalyzed cross-coupling reactions, which are indispensable for forging new carbon-carbon bonds. Reactions such as the Suzuki coupling, Heck reaction, and Sonogashira coupling leverage this reactivity to construct intricate molecular architectures. The methyl groups on the benzene ring offer additional control over steric and electronic factors, influencing the outcome of these transformations.

Sourcing High-Quality Chemical Intermediates

For laboratories and industries that rely on 1,3-dimethyl-5-iodobenzene, securing a consistent supply of high-purity material is paramount. When considering purchase options, it is vital to identify reputable suppliers and manufacturers who adhere to strict quality control standards, ensuring the ≥98.0% assay. Exploring different vendor prices and lead times is a practical step in managing research and production budgets effectively. Choosing the right source for essential chemical intermediates directly impacts the efficiency and reliability of synthetic endeavors.

Applications in Diverse Fields

The principal application of 1,3-dimethyl-5-iodobenzene is as an intermediate in the synthesis of a wide range of organic compounds. These compounds find use in sectors such as pharmaceuticals, agrochemicals, and material science, where precise molecular structures are often required for desired functions. Its role in creating complex molecules efficiently makes it a vital component in modern chemical innovation.

In conclusion, 1,3-dimethyl-5-iodobenzene serves as a critical intermediate for synthetic organic chemists. Its specific properties, coupled with reliable availability from trusted sources, empower the creation of advanced molecules essential for scientific progress and industrial development.