The field of organic chemistry is constantly evolving, with a persistent need for versatile building blocks that enable the synthesis of increasingly complex molecules. Among the vast array of reagents available, iodinated aromatic compounds stand out for their exceptional reactivity, particularly in metal-catalyzed cross-coupling reactions. 1,3-Dimethyl-5-iodobenzene, identified by CAS number 22445-41-6, is a prime example of such a valuable intermediate.

Why Iodinated Aromatics are Essential

The carbon-iodine bond is relatively weak compared to other carbon-halogen bonds, making aryl iodides highly reactive in various synthetic transformations. This enhanced reactivity is particularly beneficial in palladium-catalyzed reactions, where they often exhibit faster reaction rates and require milder conditions than their bromo- or chloro- counterparts. This makes sourcing high-quality iodinated aromatics like 1,3-dimethyl-5-iodobenzene crucial for efficient and successful synthetic campaigns.

1,3-Dimethyl-5-iodobenzene: Properties and Applications

This specific compound, 1,3-dimethyl-5-iodobenzene, features a benzene ring substituted with an iodine atom and two methyl groups. This particular arrangement provides a unique balance of electronic and steric effects, influencing its behavior in chemical reactions. It typically presents as a pink-brown to red transparent liquid with a purity assay of ≥98.0%. Its physical properties, including a boiling point around 230 °C and a density near 1.6 g/cm³, are well-documented, aiding chemists in its handling and application. The compound’s primary function is as an intermediate in organic synthesis, contributing to the construction of molecules for pharmaceuticals, agrochemicals, and materials science.

The ability to readily purchase 1,3-dimethyl-5-iodobenzene from reliable suppliers means researchers can focus on their synthesis design without concerns about the quality of their starting materials. When searching for prices or the best buy options, consider the overall value offered by a manufacturer, including consistency in purity and timely delivery.

The Importance of Purity and Availability

For chemists utilizing 1,3-dimethyl-5-iodobenzene in their work, securing a consistent supply of a high-purity product is non-negotiable. Impurities can lead to side reactions, reduced yields, and difficulties in purification, ultimately hindering research progress. Therefore, selecting a reputable supplier who ensures rigorous quality control is a critical step in the procurement process. Understanding the buy options and the market for such fine chemicals helps in planning experimental workflows efficiently.

In summary, 1,3-dimethyl-5-iodobenzene exemplifies the power and utility of iodinated aromatics in modern organic synthesis. Its availability and purity empower chemists to explore new synthetic routes and create innovative compounds, driving forward advancements in various scientific disciplines.