The success of any complex organic synthesis hinges on the availability and quality of its starting materials and intermediates. 1,3-Dimethyl-5-iodobenzene, identified by its CAS number 22445-41-6, is a significant player in this domain, acting as a pivotal intermediate for constructing a wide array of organic molecules. Its chemical structure, featuring an iodine atom and two methyl groups on an aromatic ring, endows it with unique reactivity that synthetic chemists readily exploit.

The Chemical Profile of 1,3-Dimethyl-5-iodobenzene

As a chemical intermediate, 1,3-dimethyl-5-iodobenzene (also known as 1-Iodo-3,5-dimethylbenzene) is characterized by its distinct physical and chemical properties. It typically appears as a pink-brown to red transparent liquid, with a specified purity of ≥98.0%. Key physical parameters include a density of 1.6±0.1 g/cm³ and a boiling point of approximately 229.9 °C. These specifications are vital for chemists to accurately gauge its behavior in reaction conditions and for quality assurance purposes when purchasing from suppliers.

The iodine substituent is the primary site of reactivity, making this compound highly suitable for various coupling reactions. These reactions are foundational in building complex carbon skeletons for applications ranging from pharmaceuticals to materials science. The methyl groups contribute to the molecule's steric and electronic profile, potentially influencing reaction selectivity.

Sourcing and Procurement Strategies

For research institutions and chemical companies, ensuring a reliable supply of high-quality intermediates is crucial. When looking to buy 1,3-dimethyl-5-iodobenzene, it is important to consider the reputation and quality control measures of the manufacturer or supplier. Factors such as batch-to-batch consistency, timely delivery, and competitive prices are key considerations for efficient laboratory operations. Exploring different buy options allows for optimizing the cost-effectiveness of synthetic projects.

Applications Across Industries

The application of 1,3-dimethyl-5-iodobenzene is primarily within organic synthesis. It serves as a critical starting material for the preparation of more complex molecules. Its utility in cross-coupling reactions, a staple in modern synthetic chemistry, allows for the efficient introduction of aryl groups into various molecular frameworks. This capability makes it indispensable in the research and development of new drug candidates, advanced polymers, and specialized electronic materials. The ability to procure this intermediate with a high purity assay of ≥98.0% directly impacts the success and reproducibility of these demanding applications.

In conclusion, 1,3-dimethyl-5-iodobenzene is a testament to the importance of specialized chemical intermediates. Its consistent availability and high purity, procured from reliable sources, empower chemists to push the boundaries of molecular design and synthesis, contributing to significant advancements across various scientific and industrial sectors.