Ningbo INNO Pharmchem Co., Ltd. is at the forefront of supplying specialized chemical intermediates that drive innovation in the pharmaceutical sector. Among our key offerings is 2-Bromo-5-hydroxybenzaldehyde (CAS: 2973-80-0), a compound whose significance extends across various therapeutic areas, most notably in the development of PDE4 inhibitors. The chemical industry relies heavily on such intermediates for creating advanced drug molecules.

The phosphodiesterase-4 (PDE4) enzyme plays a critical role in inflammatory pathways within the body. Inhibiting this enzyme has proven effective in treating a range of inflammatory diseases, including respiratory conditions like COPD and asthma, as well as dermatological issues like atopic dermatitis and psoriasis. Crisaborole, a prominent example, is a PDE4 inhibitor that utilizes 2-Bromo-5-hydroxybenzaldehyde as a core component in its synthesis. This makes CAS 2973-80-0 an essential piece in the puzzle of developing effective treatments for these conditions.

The chemical structure of 2-Bromo-5-hydroxybenzaldehyde, featuring both a bromine atom and a hydroxyl group on the benzaldehyde ring, provides multiple sites for chemical modification. This inherent reactivity allows chemists to build more complex molecular structures, tailoring them for specific biological targets. This versatility is what makes it such a valuable asset in the drug discovery process, enabling the creation of optimized PDE4 inhibitors with improved efficacy, safety, and pharmacokinetic profiles.

Beyond its established role in Crisaborole synthesis, researchers are continually exploring new applications for 2-Bromo-5-hydroxybenzaldehyde in developing novel therapeutic agents. Its potential in creating compounds that inhibit cancer cell growth and other proliferative diseases is an active area of research. The ability to reliably source this high-purity intermediate from manufacturers like Ningbo INNO Pharmchem Co., Ltd. is vital for advancing these research endeavors.

For companies engaged in drug discovery and development, securing a dependable supply of pharmaceutical intermediates like 2-Bromo-5-hydroxybenzaldehyde is critical. Our commitment to quality assurance and our robust production capabilities ensure that we can meet the demands of pharmaceutical research and manufacturing, supporting the advancement of innovative medicines worldwide. If you are looking to buy 2-Bromo-5-hydroxybenzaldehyde, consider the benefits of partnering with a trusted supplier.