The challenge of formulating poorly soluble drugs is a significant hurdle in pharmaceutical development. At NINGBO INNO PHARMCHEM CO.,LTD., we employ sophisticated excipients to overcome these limitations, and Sodium Starch Glycolate (SSG) plays a pivotal role in improving drug bioavailability. As a highly effective superdisintegrant, SSG's ability to accelerate tablet disintegration and dissolution is key to ensuring that these challenging APIs are effectively absorbed by the body.

Sodium Starch Glycolate (CAS No. 9063-38-1) is a specialized starch derivative engineered for rapid water uptake and swelling. This characteristic allows it to exert a strong disintegrating force on tablets. When administered, SSG-containing tablets rapidly disintegrate in the presence of gastrointestinal fluids, breaking down into numerous smaller particles. This process significantly increases the exposed surface area of the API, which is critical for poorly soluble compounds where dissolution rate often limits absorption. By facilitating faster dissolution, SSG ensures that more of the drug becomes available for absorption into the bloodstream, thereby enhancing overall bioavailability.

At NINGBO INNO PHARMCHEM CO.,LTD., we recognize the importance of SSG in formulating drugs that might otherwise exhibit low oral bioavailability. The typical inclusion of SSG at concentrations ranging from 2% to 10% provides a robust mechanism for overcoming solubility issues. Furthermore, SSG's ability to improve tablet hardness without negatively affecting disintegration means that we can produce stable dosage forms that are also highly efficient in releasing their active components. This combination of properties makes SSG an indispensable tool in our formulation arsenal.

Our expertise in utilizing Sodium Starch Glycolate extends to various tablet types, including those requiring rapid disintegration for immediate therapeutic effect. By carefully selecting and incorporating this premium excipient, NINGBO INNO PHARMCHEM CO.,LTD. consistently develops pharmaceutical products that maximize drug efficacy and patient outcomes, particularly for those APIs that present solubility challenges. The strategic use of SSG underscores our commitment to advancing pharmaceutical science and delivering effective treatments.