Exploring the Advantages of PVP/VA 64 in Pharmaceutical Tablet Formulations: A Comprehensive Guide
NINGBO INNO PHARMCHEM CO.,LTD. offers the PVP/VA 64 copolymer, a highly versatile excipient that has become a staple in the pharmaceutical industry for tablet manufacturing. Its unique properties make it particularly effective in various granulation and compression techniques, including dry granulation and roller compaction.
The inherent plasticity of the PVP/VA 64 copolymer is a significant advantage, especially in direct compression and roller compaction. Unlike some rigid binders, PVP/VA 64 allows for greater deformation during compression, which helps to reduce the incidence of capping and lamination – common defects in tablet production. This plasticity, combined with its spherical particle morphology, ensures good surface coverage and robust granule formation, leading to tablets with improved hardness and lower friability. This makes it an excellent dry binder for direct compression.
In dry granulation processes, where moisture is avoided, PVP/VA 64 performs admirably. It provides strong inter-particulate bonding, resulting in granules with excellent flowability and compressibility. This is crucial for achieving uniform tablet weight and content uniformity. Similarly, in roller compaction, the copolymer's ability to form dense compacts ensures that the resulting granules are ideal for subsequent tableting.
The PVP VA 64 copolymer binder also demonstrates good compatibility with a wide range of APIs and other excipients, ensuring formulation flexibility. Its low hygroscopicity compared to some other binders also contributes to more predictable granulation endpoints and improved storage stability of the formulated product.
NINGBO INNO PHARMCHEM CO.,LTD. provides this premium grade copovidone pharmaceutical excipient to support manufacturers in achieving optimal tablet quality. Whether you are developing directly compressed tablets, using dry granulation, or employing roller compaction, the PVP/VA 64 copolymer offers a reliable and effective solution to enhance your tablet formulation's performance and manufacturing efficiency. When you choose to buy PVP/VA 64 from us, you are investing in a proven excipient that contributes to the success of your pharmaceutical products.
Perspectives & Insights
Quantum Pioneer 24
“provides this premium grade copovidone pharmaceutical excipient to support manufacturers in achieving optimal tablet quality.”
Bio Explorer X
“Whether you are developing directly compressed tablets, using dry granulation, or employing roller compaction, the PVP/VA 64 copolymer offers a reliable and effective solution to enhance your tablet formulation's performance and manufacturing efficiency.”
Nano Catalyst AI
“When you choose to buy PVP/VA 64 from us, you are investing in a proven excipient that contributes to the success of your pharmaceutical products.”