Sourcing High-Purity 4-Carboxy-3-fluorophenylboronic Acid: A Guide for Researchers
In the realm of advanced organic chemistry and pharmaceutical development, the quality and availability of specific chemical building blocks are critical. 4-Carboxy-3-fluorophenylboronic acid (CAS 120153-08-4) stands out as a highly valuable compound, primarily due to its utility as a pharmaceutical intermediate and its proficiency in various coupling reactions. For researchers and chemical manufacturers, understanding where and how to procure this compound efficiently is key to project success. This article provides insights into sourcing this important material, emphasizing the benefits of partnering with experienced manufacturers.
The significance of 4-Carboxy-3-fluorophenylboronic acid in chemical synthesis stems from its unique molecular structure. It features a phenyl ring substituted with a carboxylic acid group at the 4-position and a fluorine atom at the 3-position, along with the reactive boronic acid group. This combination makes it an excellent substrate for Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern synthetic organic chemistry. These reactions are instrumental in creating complex molecular frameworks, which are essential for the design and synthesis of new drugs and advanced materials. The fluorine substitution can also influence the electronic properties and metabolic stability of the resulting molecules, making it a preferred choice for certain pharmaceutical applications.
When considering the purchase of 4-Carboxy-3-fluorophenylboronic acid, researchers often prioritize high purity to ensure predictable reaction outcomes and to avoid potential complications from impurities. Specifications such as an assay of ≥98.0% are standard indicators of quality. Its physical characteristics, including being a white powder and its solubility in water, contribute to its ease of use in laboratory settings. For those looking to buy this chemical, identifying reliable suppliers is crucial. Manufacturers in China, such as NINGBO INNO PHARMCHEM CO.,LTD., have established themselves as key providers of fine chemicals, offering competitive pricing and robust quality control measures. Sourcing directly from such manufacturers can streamline the procurement process and ensure a consistent supply chain.
The demand for specialized intermediates like 4-Carboxy-3-fluorophenylboronic acid continues to grow as research into new therapeutics and materials accelerates. By understanding the product's properties and applications, and by partnering with trusted suppliers, researchers can effectively integrate this versatile compound into their synthetic strategies. Investing in high-quality pharmaceutical intermediates is an investment in the success and efficiency of your research and development efforts.
Perspectives & Insights
Alpha Spark Labs
“These reactions are instrumental in creating complex molecular frameworks, which are essential for the design and synthesis of new drugs and advanced materials.”
Future Pioneer 88
“The fluorine substitution can also influence the electronic properties and metabolic stability of the resulting molecules, making it a preferred choice for certain pharmaceutical applications.”
Core Explorer Pro
“When considering the purchase of 4-Carboxy-3-fluorophenylboronic acid, researchers often prioritize high purity to ensure predictable reaction outcomes and to avoid potential complications from impurities.”