Fmoc-4-Nitro-L-Phenylalanine: Synthesis, Properties, and Applications in Peptide Chemistry
Discover the key properties and diverse applications of Fmoc-4-Nitro-L-Phenylalanine in modern peptide synthesis and drug discovery.
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Fmoc-4-Nitro-L-Phenylalanine
Fmoc-4-Nitro-L-Phenylalanine is a crucial building block for advanced peptide synthesis, enabling the introduction of specific functionalities and properties into peptide chains. Its unique structure makes it invaluable for researchers developing novel therapeutic agents and biochemical probes.
- Leverage the power of peptide synthesis reagents by incorporating 4-nitrophenylalanine residue into your sequences.
- Explore the potential of VLA-4 integrin antagonists with Fmoc-4-Nitro-L-Phenylalanine as a key intermediate.
- Utilize this compound for its dual role as an IR probe or FRET quencher in advanced biochemical studies.
- Discover its utility in the synthesis of analogs of kahalalide F, pushing the boundaries of chemical innovation.
Key Advantages
High Purity and Quality
Ensuring exceptional purity, typically ≥98%, makes this compound reliable for sensitive applications like peptide synthesis.
Versatile Intermediate
Serves as a critical intermediate in synthesizing complex molecules, including potential VLA-4 integrin antagonists for therapeutic research.
Enhanced Research Capabilities
The nitro group allows for unique applications, such as acting as an IR probe or FRET pair component, significantly enhancing biochemical research capabilities.
Key Applications
Peptide Synthesis
Facilitates the incorporation of modified amino acids, vital for developing peptides with specific biological activities and properties, drawing from extensive peptide synthesis reagents knowledge.
Drug Discovery
Acts as a crucial building block in the synthesis of novel drug candidates, particularly those targeting inflammatory pathways, informed by medicinal chemistry principles.
Biochemical Research
Enables detailed studies of protein function and interactions, utilizing its properties as an IR probe or FRET quencher within various biochemical research contexts.
Chemical Synthesis
Serves as a versatile starting material or intermediate in the creation of complex organic molecules, highlighting its role in organic synthesis.