The field of fine chemicals relies heavily on specialized building blocks that enable the construction of complex molecules. 2-Fluoro-5-nitroanisole (CAS 454-16-0) is a prime example of such a compound, valued for its reactivity and potential in diverse synthetic pathways. This article aims to provide a detailed overview of its properties, applications, and the considerations involved in its procurement, especially from leading manufacturers.

Chemical Profile and Properties

2-Fluoro-5-nitroanisole, also referred to by its IUPAC name 1-fluoro-2-methoxy-4-nitrobenzene, boasts a molecular formula of C7H6FNO3 and a molecular weight of 171.13. It typically appears as a light yellow crystalline solid. Key physical properties include a melting point of 69-71°C and a predicted boiling point of approximately 270.3°C. Its solubility in solvents like chloroform and methanol is noted as slight. Safety data indicates it as an irritant, requiring appropriate handling precautions.

The Importance of Purity in Synthesis

For any chemical intermediate, purity is paramount, and 2-Fluoro-5-nitroanisole is no exception. Manufacturers strive for purity levels of 99.5% or higher to ensure that reactions proceed as expected and that the final products meet stringent quality standards. Impurities can lead to side reactions, reduced yields, and difficulties in purification. Therefore, when considering the purchase of this chemical, verifying the purity specifications is a critical step. Reliable chemical synthesis intermediates are the backbone of successful R&D.

Applications Across Industries

The structural features of 2-Fluoro-5-nitroanisole make it a valuable component in several key industries:

  • Pharmaceuticals: It acts as a precursor for creating complex organic molecules that are integral to drug discovery and development. Its fluorinated nature can influence pharmacokinetic properties like bioavailability and metabolic stability.
  • Agrochemicals: This compound is instrumental in the synthesis of innovative pesticides and herbicides, contributing to more efficient and environmentally conscious agricultural practices.
  • Research Laboratories: The compound is widely used in academic and industrial research for developing new synthetic methodologies and exploring novel chemical entities. When researching the price of 2-Fluoro-5-nitroanisole, it's often linked to its critical role in advancing scientific knowledge.

Sourcing Strategy for 2-Fluoro-5-nitroanisole

When looking to buy 2-Fluoro-5-nitroanisole, particularly if you are searching for reliable chemical suppliers in China, it is essential to partner with established companies. NINGBO INNO PHARMCHEM CO.,LTD. positions itself as a trusted manufacturer and supplier, committed to delivering high-grade fine chemicals. Understanding the CAS 454-16-0 specifications and the general utility of fluorinated intermediates will guide your sourcing decisions.