In the realm of organic synthesis, the availability of versatile and reactive chemical intermediates is crucial for innovation. 2-Fluoro-5-nitroanisole, identified by CAS number 454-16-0, stands out as a significant building block, enabling the creation of sophisticated molecular architectures. This article explores the multifaceted applications of this compound and highlights its importance in advancing chemical research and manufacturing.

Understanding 2-Fluoro-5-nitroanisole's Chemical Structure and Properties

With the molecular formula C7H6FNO3 and a molecular weight of 171.13 g/mol, 2-Fluoro-5-nitroanisole is characterized by the presence of a fluorine atom and a nitro group on a methoxybenzene core. This unique combination of functional groups dictates its chemical behavior and utility. Typically presented as a light yellow solid, it possesses a melting point of 69-71°C. Its solubility in common organic solvents is moderate, and it is generally handled as a stable compound under recommended storage conditions.

Role as a Key Intermediate in Synthesis

The true value of 2-Fluoro-5-nitroanisole lies in its function as a versatile intermediate for a wide range of chemical transformations. Chemists leverage its reactive sites to introduce complex functionalities into target molecules. This makes it particularly useful in:

  • Drug Discovery: The compound is a precursor for synthesizing various pharmaceutical candidates, where the fluorine atom can modulate lipophilicity and metabolic stability, and the nitro group can be reduced or further functionalized. Understanding the buy 2-Fluoro-5-nitroanisole price is essential for budgeting R&D.
  • Agrochemical Design: Its structure is beneficial for developing new agrochemicals, such as insecticides and herbicides, by providing a scaffold that can be modified to achieve specific biological activities.
  • Materials Science: Researchers utilize it in the synthesis of advanced materials, including polymers, dyes, and electronic components, where its specific electronic and structural properties are advantageous.
  • Fine Chemical Production: As a fundamental building block, it supports the broader fine chemical industry, contributing to the synthesis of custom molecules for various niche applications.

Sourcing and Quality Assurance

For any laboratory or manufacturing facility, securing a consistent supply of high-purity 2-Fluoro-5-nitroanisole is crucial. When searching for suppliers, it's important to look for those that provide detailed product specifications and Certificates of Analysis (CoA). Companies like NINGBO INNO PHARMCHEM CO.,LTD. are dedicated to supplying top-tier chemical intermediates, ensuring that clients receive materials that meet rigorous quality standards. Enquiries about 2-Fluoro-5-nitroanisole price and availability are standard procedures for businesses relying on this key intermediate.

Conclusion

2-Fluoro-5-nitroanisole (CAS 454-16-0) is an indispensable tool in the arsenal of modern organic chemists. Its unique chemical properties and versatility as an intermediate make it vital for progress in pharmaceuticals, agrochemicals, and materials science. By partnering with reliable manufacturers, researchers and industries can ensure access to this essential compound, driving forward innovation in chemical synthesis.