In the relentless pursuit of novel therapeutics and improved drug formulations, the availability of specialized chemical building blocks is indispensable. Azepane (CAS 111-49-9) has emerged as a compound of significant interest within the pharmaceutical industry due to its versatile chemical structure and crucial role in the synthesis of various active pharmaceutical ingredients (APIs). This article will explore the significance of Azepane as a building block, its applications in pharmaceutical innovation, and the importance of securing a reliable supply chain for this vital chemical intermediate.

Azepane, a seven-membered heterocyclic amine, is characterized by its cyclic secondary amine structure. In its pure form, it presents as a colorless to light yellow liquid, with a stated purity of ≥98.0%. Its chemical formula is C6H13N, and its CAS number is 111-49-9, serving as a unique identifier for researchers and manufacturers globally. The compound’s physical properties, such as its liquid state and moderate boiling point, facilitate its handling and integration into complex synthetic pathways.

The true value of Azepane lies in its utility as a synthetic intermediate. It is particularly recognized for its application in the creation of Bazedoxifene, a significant pharmaceutical used in the management of osteoporosis. The azepane ring provides a core scaffold that imparts specific pharmacological properties to the final drug molecule. This reliance on Azepane underscores its importance not just as a chemical reagent, but as an enabler of medical advancements. For companies involved in the development or manufacturing of such drugs, sourcing high-quality Azepane is a critical step.

Beyond specific drug synthesis, Azepane's inherent reactivity as a secondary amine allows for its incorporation into a broad spectrum of organic molecules. This makes it a valuable component for drug discovery efforts, where chemists often explore novel heterocyclic structures to identify new therapeutic leads. The ability to buy Azepane from reliable manufacturers ensures that R&D projects can proceed without interruption, facilitating innovation in areas ranging from oncology to infectious diseases. The availability of Hexahydroazepine for sale from experienced chemical suppliers is thus crucial for the progression of pharmaceutical research.

For pharmaceutical companies and contract research organizations (CROs), establishing a consistent and dependable supply of Azepane is paramount. Manufacturers, especially those based in China, often provide Azepane in bulk quantities (e.g., 200 kg drums) and can offer competitive pricing. However, the focus should remain on quality and reliability. When seeking to purchase Azepane, due diligence in vetting suppliers for their quality control systems, production capacity, and logistical capabilities is essential. Understanding the Azepane price in context of these factors will lead to more strategic procurement decisions.

In conclusion, Azepane serves as a foundational building block in pharmaceutical innovation, facilitating the synthesis of vital medications and enabling the exploration of new chemical entities. Its reliable supply, guaranteed by reputable manufacturers and suppliers, is critical for the advancement of drug discovery and development. As the pharmaceutical landscape continues to evolve, the demand for high-quality intermediates like Azepane will undoubtedly persist, reinforcing its status as an indispensable component in modern medicine manufacturing.