Selecting the appropriate biotinylation agent is a critical decision for researchers aiming to achieve efficient and specific labeling of biomolecules. Sulfo-NHS-LC-Biotin (CAS 191671-46-2) is a standout choice due to its unique combination of water solubility and amine reactivity. As a prominent manufacturer and supplier of fine chemicals, we understand the nuances of reagent selection and are proud to offer this vital tool for your research. When you decide to buy Sulfo-NHS-LC-Biotin, consider its advantages for your specific application.

Sulfo-NHS-LC-Biotin is designed to react with primary amine groups present in proteins, peptides, antibodies, and other amine-bearing molecules. The N-hydroxysuccinimide (NHS) ester moiety is highly reactive towards amines, forming a stable amide bond under mild conditions, typically at a pH range of 7.0-9.0. The key differentiator for this reagent is the 'Sulfo' modification, which significantly enhances its solubility in aqueous buffers. This property is invaluable for biological applications where the integrity of biomolecules must be maintained, often precluding the use of organic solvents. Furthermore, the 'LC' (long-chain) spacer in the molecule helps to reduce steric hindrance, potentially improving the binding efficiency of the biotin label to its avidin or streptavidin counterparts, thus leading to stronger signals in detection assays.

The applications where Sulfo-NHS-LC-Biotin proves exceptionally useful include:

  • Antibody Labeling for Diagnostic Assays: Its water solubility and amine reactivity make it ideal for labeling antibodies used in sensitive diagnostic tests like ELISA and lateral flow assays.
  • Protein Conjugation for Research: Researchers use it to attach biotin to proteins for various purposes, including protein arrays, affinity purification, and studying protein-protein interactions.
  • Cell-Based Assays: When used to label cell surface proteins or ligands, it facilitates studies in cell adhesion, signaling, and imaging.
  • Development of Biosensors: Biotinylated molecules can be immobilized onto biosensor surfaces to detect specific analytes.

Our company, a reputable Sulfo-NHS-LC-Biotin manufacturer and supplier in China, ensures that our product meets stringent purity standards (≥99%). This commitment to quality is vital for researchers who depend on consistent and reliable reagents for their experimental success. We strive to offer competitive Sulfo-NHS-LC-Biotin price options, making advanced scientific tools accessible. Choosing us as your primary CAS 191671-46-2 supplier means you are opting for quality, reliability, and efficiency in your procurement process.

To preserve its activity, Sulfo-NHS-LC-Biotin should be stored at -20°C. Its ease of handling in aqueous solutions significantly streamlines experimental protocols. For any lab focused on precise biomolecule labeling and conjugation, securing a dependable source for high-quality Sulfo-NHS-LC-Biotin is essential. We are dedicated to supporting your scientific exploration with superior chemical reagents and responsive service.