Sulfo-NHS-LC-Biotin: A Key Reagent for Bioconjugation Success
In the realm of biochemical research and development, successful bioconjugation is often the key to unlocking novel insights and creating advanced diagnostic and therapeutic tools. Sulfo-NHS-LC-Biotin (CAS 191671-46-2) is a pivotal reagent that facilitates this process, enabling the precise attachment of biotin to various biomolecules. As a specialized manufacturer and supplier of high-quality fine chemicals from China, we understand the needs of researchers and are dedicated to providing reliable access to this essential compound. For those looking to buy Sulfo-NHS-LC-Biotin, understanding its benefits is the first step.
Sulfo-NHS-LC-Biotin is characterized by its water solubility and amine reactivity. The succinimidyl ester group readily reacts with primary amines found in molecules like proteins, peptides, and antibodies, forming a stable amide linkage. This reaction is efficient and typically performed under physiological pH conditions, making it compatible with a wide range of biological samples. The 'Sulfo' modification imparts water solubility, simplifying reaction setup by eliminating the need for potentially destabilizing organic co-solvents. The 'LC' or long-chain spacer helps to ensure that the biotin moiety is accessible for binding to avidin or streptavidin, thereby optimizing signal detection and purification efficiency.
The utility of Sulfo-NHS-LC-Biotin is extensive and critical for various scientific endeavors:
- Protein and Antibody Labeling: It is widely used to biotinylate proteins and antibodies for applications such as ELISA, Western blotting, immunohistochemistry, and flow cytometry, enhancing detection sensitivity.
- Biomolecule Immobilization: Biotinylated molecules can be immobilized onto avidin- or streptavidin-coated surfaces for various assay formats or for creating affinity matrices.
- Diagnostics Development: Its role in creating sensitive detection systems makes it valuable for developing in vitro diagnostic assays.
- Research Tool: It serves as a fundamental building block for creating tagged molecules in fundamental research across molecular biology, immunology, and cell biology.
As a leading Sulfo-NHS-LC-Biotin supplier and manufacturer, we prioritize product quality and consistency. We offer Sulfo-NHS-LC-Biotin with a guaranteed purity of ≥99%, ensuring that your experiments yield reliable and reproducible results. Our position as a China-based manufacturer allows us to provide competitive Sulfo-NHS-LC-Biotin price options, making advanced reagents accessible to a broader research community. When seeking a dependable CAS 191671-46-2 supplier, our company stands ready to meet your needs.
Proper handling and storage are key to maintaining the activity of Sulfo-NHS-LC-Biotin; storage at -20°C is standard. Its ease of use in aqueous solutions makes it a preferred choice for many researchers. For laboratories requiring a consistent and high-quality source of biotinylation reagents, partnering with an experienced chemical supplier is essential. We are committed to supporting your scientific breakthroughs by providing superior chemical products.
Perspectives & Insights
Core Pioneer 24
“Diagnostics Development: Its role in creating sensitive detection systems makes it valuable for developing in vitro diagnostic assays.”
Silicon Explorer X
“Research Tool: It serves as a fundamental building block for creating tagged molecules in fundamental research across molecular biology, immunology, and cell biology.”
Quantum Catalyst AI
“As a leading Sulfo-NHS-LC-Biotin supplier and manufacturer, we prioritize product quality and consistency.”