Coelenterazine, identified by CAS number 55779-48-1, is a naturally occurring luciferin that plays a critical role in bioluminescence across many marine species. Beyond its biological significance, its unique chemical structure and properties have made it a subject of extensive research, particularly in the areas of chemical synthesis and diverse scientific applications. Understanding its chemistry is key to unlocking its full potential.

The chemical synthesis of Coelenterazine is a complex process that has been refined over years of scientific investigation. While originally isolated from marine organisms, synthetic routes now provide reliable access to this crucial molecule. These synthesis pathways are vital for ensuring a consistent and high-purity supply, essential for researchers who depend on Coelenterazine for their experiments. NINGBO INNO PHARMCHEM CO.,LTD., as a dedicated manufacturer in China, specializes in the chemical synthesis of Coelenterazine, ensuring the quality and availability required by the scientific community.

The primary application of Coelenterazine stems from its role as a substrate for bioluminescent enzymes like Renilla luciferase and aequorin. In assays measuring intracellular calcium concentrations, aequorin binds to Ca2+ ions, triggering the oxidation of Coelenterazine and emitting light. This makes Coelenterazine indispensable for studying cellular signaling pathways. For scientists needing to purchase Coelenterazine for these sensitive assays, the purity and consistent performance of the chemical are non-negotiable.

Furthermore, Coelenterazine is a cornerstone of bioluminescent reporter gene systems. When coupled with Renilla luciferase, it enables highly sensitive detection of gene expression. This application is widely utilized in drug discovery, where researchers screen vast numbers of compounds for their ability to modulate gene activity. The efficiency of these screening processes relies heavily on the availability of a stable and reactive Coelenterazine supply. NINGBO INNO PHARMCHEM CO.,LTD. offers Coelenterazine that meets the rigorous demands of high-throughput screening.

Research into Coelenterazine analogues continues to expand its utility. Scientists are synthesizing derivatives with modified chemical structures to achieve different bioluminescent outputs, such as shifted emission wavelengths or enhanced stability. These advancements are crucial for developing more sophisticated bioluminescent imaging techniques, including multicolor assays and deep-tissue imaging. The ability to buy these specialized Coelenterazine compounds empowers researchers to push the boundaries of scientific inquiry.

In summary, Coelenterazine (CAS: 55779-48-1) is a molecule of significant chemical and biological importance. Its synthesis and applications in bioluminescence imaging, calcium measurements, and reporter gene assays are critical to modern life science research. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-quality Coelenterazine and its derivatives, ensuring researchers have access to the essential tools they need. If you are looking to purchase Coelenterazine, consider our expertise and commitment to scientific excellence.