Procuring 4-Nitrobenzenesulfonyl Chloride (CAS 98-74-8): A Manufacturer's Perspective
4-Nitrobenzenesulfonyl chloride, identified by CAS number 98-74-8, is a pivotal chemical intermediate with a wide range of applications in organic synthesis. As a leading manufacturer in China, NINGBO INNO PHARMCHEM CO.,LTD. plays a key role in supplying this essential compound. This article explores its fundamental properties, its critical role in peptide synthesis, and the advantages of procuring it from established Chinese suppliers, including details on how to buy 4-Nitrobenzenesulfonyl chloride online.
Chemical Profile and Properties
4-Nitrobenzenesulfonyl chloride (C6H4ClNO4S) is typically supplied as a yellow to brown powder, with a molecular weight of 221.62 g/mol. Its melting point is usually between 75-81°C. The compound's reactivity stems from the sulfonyl chloride functional group, making it a versatile reagent for introducing the nitrobenzenesulfonyl moiety into various organic molecules. This characteristic is particularly exploited in the preparation of N-nosyl-protected amino acids, which are critical for controlled peptide chain elongation in peptide synthesis. The high purity, often exceeding 98%, offered by manufacturers like NINGBO INNO PHARMCHEM CO.,LTD., is essential for achieving reliable and reproducible results in complex chemical reactions.
Applications and Market Demand
The primary market driver for 4-Nitrobenzenesulfonyl chloride is its application in peptide synthesis. As a precursor for N-Nosyl-α-amino acids, it supports the production of therapeutic peptides, research peptides, and other biologically active molecules. The growing demand in the pharmaceutical and biotechnology sectors for advanced peptide-based products directly translates into a sustained need for this intermediate. Furthermore, its utility extends to other areas of organic synthesis, where it acts as a building block for specialty chemicals. The efficient manufacturing capabilities in China have made it easier for researchers and industries globally to access this compound.
Procurement and Safety
For businesses seeking to purchase 4-Nitrobenzenesulfonyl chloride, partnering with experienced manufacturers such as NINGBO INNO PHARMCHEM CO.,LTD. offers numerous benefits, including competitive pricing and consistent quality assurance. When sourcing online, it's crucial to verify the supplier's credentials and product specifications. Safety is a paramount concern when dealing with 4-Nitrobenzenesulfonyl chloride due to its corrosive nature. Users must strictly adhere to safety guidelines, including wearing appropriate personal protective equipment (PPE) such as gloves, eye protection, and protective clothing. Working in a well-ventilated area is also critical to avoid inhalation. The Safety Data Sheet (SDS) provided by the manufacturer contains vital information on handling, storage, and emergency procedures. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing comprehensive product and safety information.
In conclusion, 4-Nitrobenzenesulfonyl chloride (CAS 98-74-8) is an indispensable fine chemical intermediate, particularly for peptide synthesis. Its procurement from reliable manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. ensures quality and availability, while strict adherence to safety protocols guarantees its effective and responsible use in chemical synthesis.
Chemical Profile and Properties
4-Nitrobenzenesulfonyl chloride (C6H4ClNO4S) is typically supplied as a yellow to brown powder, with a molecular weight of 221.62 g/mol. Its melting point is usually between 75-81°C. The compound's reactivity stems from the sulfonyl chloride functional group, making it a versatile reagent for introducing the nitrobenzenesulfonyl moiety into various organic molecules. This characteristic is particularly exploited in the preparation of N-nosyl-protected amino acids, which are critical for controlled peptide chain elongation in peptide synthesis. The high purity, often exceeding 98%, offered by manufacturers like NINGBO INNO PHARMCHEM CO.,LTD., is essential for achieving reliable and reproducible results in complex chemical reactions.
Applications and Market Demand
The primary market driver for 4-Nitrobenzenesulfonyl chloride is its application in peptide synthesis. As a precursor for N-Nosyl-α-amino acids, it supports the production of therapeutic peptides, research peptides, and other biologically active molecules. The growing demand in the pharmaceutical and biotechnology sectors for advanced peptide-based products directly translates into a sustained need for this intermediate. Furthermore, its utility extends to other areas of organic synthesis, where it acts as a building block for specialty chemicals. The efficient manufacturing capabilities in China have made it easier for researchers and industries globally to access this compound.
Procurement and Safety
For businesses seeking to purchase 4-Nitrobenzenesulfonyl chloride, partnering with experienced manufacturers such as NINGBO INNO PHARMCHEM CO.,LTD. offers numerous benefits, including competitive pricing and consistent quality assurance. When sourcing online, it's crucial to verify the supplier's credentials and product specifications. Safety is a paramount concern when dealing with 4-Nitrobenzenesulfonyl chloride due to its corrosive nature. Users must strictly adhere to safety guidelines, including wearing appropriate personal protective equipment (PPE) such as gloves, eye protection, and protective clothing. Working in a well-ventilated area is also critical to avoid inhalation. The Safety Data Sheet (SDS) provided by the manufacturer contains vital information on handling, storage, and emergency procedures. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing comprehensive product and safety information.
In conclusion, 4-Nitrobenzenesulfonyl chloride (CAS 98-74-8) is an indispensable fine chemical intermediate, particularly for peptide synthesis. Its procurement from reliable manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. ensures quality and availability, while strict adherence to safety protocols guarantees its effective and responsible use in chemical synthesis.
Perspectives & Insights
Agile Reader One
“offers numerous benefits, including competitive pricing and consistent quality assurance.”
Logic Vision Labs
“When sourcing online, it's crucial to verify the supplier's credentials and product specifications.”
Molecule Origin 88
“Safety is a paramount concern when dealing with 4-Nitrobenzenesulfonyl chloride due to its corrosive nature.”