4-Nitrobenzenesulfonyl Chloride (CAS 98-74-8): Properties, Safety, and Supply Chain
4-Nitrobenzenesulfonyl chloride, identified by the CAS number 98-74-8, is a chemical compound of significant industrial importance, primarily serving as a fine chemical intermediate. Its distinctive properties and reactive nature make it a sought-after material in various synthetic pathways. This article explores the physical characteristics of this compound, crucial safety measures for its handling, and its position within the global chemical supply chain, highlighting its procurement from China.
Physical and Chemical Profile
The compound presents as a yellow to brown powder, a visual characteristic that distinguishes it. Its molecular formula is C6H4ClNO4S, with a molecular weight of 221.62 g/mol. Key physical properties include a melting point typically ranging from 75-81°C. Chemically, the presence of the sulfonyl chloride group makes it a reactive species, susceptible to nucleophilic attack. This reactivity is leveraged in its applications, where it is used to introduce the nitrobenzenesulfonyl moiety into other molecules. The purity level, often specified as ≥98%, is critical for its reliable performance in chemical synthesis. NINGBO INNO PHARMCHEM CO.,LTD. and other manufacturers in China are primary sources for this compound, ensuring consistent quality for customers.
Safety Protocols for Handling
4-Nitrobenzenesulfonyl chloride is classified as a hazardous substance, specifically noted for its corrosive properties. Safe handling is therefore of utmost importance. Standard safety precautions include wearing appropriate personal protective equipment (PPE) such as chemical-resistant gloves, safety goggles, and protective clothing to prevent skin and eye contact. Operations should be conducted in areas with good ventilation, preferably under a fume hood, to minimize exposure to dust. In the event of accidental contact, immediate and thorough washing with water is recommended. Proper storage in a cool, dry environment, away from moisture, is also essential. Adherence to the guidelines provided in the Material Safety Data Sheet (MSDS) is crucial for all users of this chemical, a resource often provided by suppliers like NINGBO INNO PHARMCHEM CO.,LTD.
Role in the Chemical Industry and Supply Chain
As a fine chemical intermediate, 4-Nitrobenzenesulfonyl chloride plays a vital role in the broader chemical industry. Its primary use in the preparation of N-Nosyl-α-amino acids for peptide synthesis highlights its significance in the pharmaceutical and biotech sectors. It also serves as a building block for other specialty chemicals. The efficiency and cost-effectiveness of its production in countries like China have made it a globally accessible reagent. For businesses looking to buy 4-Nitrobenzenesulfonyl chloride, sourcing from established Chinese manufacturers provides a strategic advantage in terms of price and availability. NINGBO INNO PHARMCHEM CO.,LTD. is a notable entity in this supply chain.
In conclusion, 4-Nitrobenzenesulfonyl chloride (CAS 98-74-8) is a vital chemical intermediate with specific physical properties and significant reactivity, making it invaluable for synthesis. Prioritizing safety and understanding its role in the supply chain are key to its successful application.
Physical and Chemical Profile
The compound presents as a yellow to brown powder, a visual characteristic that distinguishes it. Its molecular formula is C6H4ClNO4S, with a molecular weight of 221.62 g/mol. Key physical properties include a melting point typically ranging from 75-81°C. Chemically, the presence of the sulfonyl chloride group makes it a reactive species, susceptible to nucleophilic attack. This reactivity is leveraged in its applications, where it is used to introduce the nitrobenzenesulfonyl moiety into other molecules. The purity level, often specified as ≥98%, is critical for its reliable performance in chemical synthesis. NINGBO INNO PHARMCHEM CO.,LTD. and other manufacturers in China are primary sources for this compound, ensuring consistent quality for customers.
Safety Protocols for Handling
4-Nitrobenzenesulfonyl chloride is classified as a hazardous substance, specifically noted for its corrosive properties. Safe handling is therefore of utmost importance. Standard safety precautions include wearing appropriate personal protective equipment (PPE) such as chemical-resistant gloves, safety goggles, and protective clothing to prevent skin and eye contact. Operations should be conducted in areas with good ventilation, preferably under a fume hood, to minimize exposure to dust. In the event of accidental contact, immediate and thorough washing with water is recommended. Proper storage in a cool, dry environment, away from moisture, is also essential. Adherence to the guidelines provided in the Material Safety Data Sheet (MSDS) is crucial for all users of this chemical, a resource often provided by suppliers like NINGBO INNO PHARMCHEM CO.,LTD.
Role in the Chemical Industry and Supply Chain
As a fine chemical intermediate, 4-Nitrobenzenesulfonyl chloride plays a vital role in the broader chemical industry. Its primary use in the preparation of N-Nosyl-α-amino acids for peptide synthesis highlights its significance in the pharmaceutical and biotech sectors. It also serves as a building block for other specialty chemicals. The efficiency and cost-effectiveness of its production in countries like China have made it a globally accessible reagent. For businesses looking to buy 4-Nitrobenzenesulfonyl chloride, sourcing from established Chinese manufacturers provides a strategic advantage in terms of price and availability. NINGBO INNO PHARMCHEM CO.,LTD. is a notable entity in this supply chain.
In conclusion, 4-Nitrobenzenesulfonyl chloride (CAS 98-74-8) is a vital chemical intermediate with specific physical properties and significant reactivity, making it invaluable for synthesis. Prioritizing safety and understanding its role in the supply chain are key to its successful application.
Perspectives & Insights
Data Seeker X
“The purity level, often specified as ≥98%, is critical for its reliable performance in chemical synthesis.”
Chem Reader AI
“and other manufacturers in China are primary sources for this compound, ensuring consistent quality for customers.”
Agile Vision 2025
“Safety Protocols for Handling 4-Nitrobenzenesulfonyl chloride is classified as a hazardous substance, specifically noted for its corrosive properties.”