For scientists and procurement managers in the pharmaceutical, biotech, and chemical industries, sourcing high-quality reagents is a cornerstone of successful research and development. N-Succinimidyl 11-(maleimido)undecanoate (CAS 87981-04-2) is a prime example of such a critical compound, widely employed in sophisticated bioconjugation strategies. As a manufacturer and supplier, we understand the discerning needs of our clients and the importance of providing a reagent that meets stringent purity and performance standards.

N-Succinimidyl 11-(maleimido)undecanoate is a bifunctional molecule, meaning it possesses two distinct reactive groups: a maleimide and an N-hydroxysuccinimide (NHS) ester. The maleimide group is specifically designed to react with thiols (sulfhydryl groups), typically found in cysteine residues of proteins. This reaction forms a stable thioether bond. The NHS ester, on the other hand, readily reacts with primary amines, such as those found in lysine residues or at the N-terminus of proteins, creating a robust amide linkage.

The efficacy of this linker in applications like Antibody-Drug Conjugates (ADCs), protein labeling, and the development of diagnostic assays directly depends on its purity and the reliability of its functional groups. When you are looking to buy N-Succinimidyl 11-(maleimido)undecanoate, it is crucial to partner with suppliers who can guarantee high purity, often specified as ≥98% by HPLC. This ensures predictable reaction kinetics and minimizes the risk of introducing unwanted byproducts or cross-reactivity into your sensitive biomolecular constructs.

As a dedicated N-Succinimidyl 11-(maleimido)undecanoate supplier in China, our focus is on maintaining rigorous quality control throughout the manufacturing process. This commitment translates into a consistent product that our clients can trust. We recognize that the price of N-Succinimidyl 11-(maleimido)undecanoate is an important consideration for procurement budgets, but it should always be balanced with quality assurance. Investing in a higher purity product from a reputable source often leads to more successful experiments and fewer wasted resources.

Key factors to consider when procuring N-Succinimidyl 11-(maleimido)undecanoate:

  • Purity: High purity (≥98% HPLC) is essential for specific and efficient conjugation.
  • CAS Number: Ensure the CAS number 87981-04-2 is correctly identified.
  • Functional Group Integrity: Both the maleimide and NHS ester groups must be intact and reactive.
  • Stability: Proper storage conditions (typically 2-8°C) are vital to maintain product integrity.
  • Documentation: Availability of Certificates of Analysis (CoA) and Safety Data Sheets (SDS) is non-negotiable for pharmaceutical and research applications.
  • Supplier Reliability: Partner with manufacturers who have a proven track record and robust supply chain management.

The versatility of N-Succinimidyl 11-(maleimido)undecanoate makes it a staple in many advanced research areas. It is used to create targeted therapies, develop diagnostic tools, modify peptides, and functionalize materials. For instance, the ten-carbon linker arm provides optimal spacing and flexibility, which is often beneficial in complex bioconjugation schemes.

In conclusion, procuring N-Succinimidyl 11-(maleimido)undecanoate requires a careful selection of suppliers. Prioritizing purity, consistent quality, and reliable documentation from experienced manufacturers ensures that your bioconjugation projects will be built on a solid foundation. We are proud to be a leading provider of this critical reagent, supporting scientific innovation with quality and dependability.