The efficiency and success of modern chemical manufacturing hinge on the availability and quality of key intermediates. 3-Chloro-4-fluorotoluene, identified by its CAS number 1513-25-3, is a prominent example of such a compound, offering significant advantages in the synthesis of pharmaceuticals and agrochemicals. This article explores its properties, applications, and the strategic benefits of sourcing it from China.

Chemical Profile and Properties

3-Chloro-4-fluorotoluene is characterized by the molecular formula C7H6ClF and a molecular weight of 144.57400. As a liquid, it typically appears colorless to light yellow and transparent. Its physical properties, including a boiling point of 167°C and a flash point of 45.4°C, classify it as a flammable substance, requiring adherence to specific safety protocols during handling and storage. The density is recorded at 1.358 g/cm³. The molecule’s structure, featuring strategically placed chlorine and fluorine atoms on a toluene ring, provides unique reactivity, making it an exceptionally versatile intermediate for a broad spectrum of chemical transformations. This versatility is crucial for synthetic chemists aiming to build complex molecular architectures.

Applications in the Pharmaceutical Industry

In the pharmaceutical sector, 3-Chloro-4-fluorotoluene is highly valued as a precursor for creating Active Pharmaceutical Ingredients (APIs). Medicinal chemists leverage its specific structure to synthesize drug candidates with enhanced efficacy, improved metabolic stability, and better pharmacokinetic profiles. The compound’s role in pharmaceutical intermediates synthesis is critical for the development of new treatments for various diseases. Sourcing this intermediate from manufacturers in China, known for their robust chemical production capabilities, ensures access to high-purity material (typically ≥98% with ≤0.5% water content), which is essential for consistent and reliable drug manufacturing.

Contribution to the Agrochemical Sector

The agrochemical industry also relies heavily on intermediates like 3-Chloro-4-fluorotoluene for developing advanced crop protection solutions. It serves as a key building block in the synthesis of herbicides, pesticides, and fungicides, which are vital for maintaining agricultural yields and ensuring global food security. The specific functionalities that can be introduced using this intermediate allow for the creation of more targeted and environmentally sound agrochemicals. Partnering with reliable agrochemical intermediate suppliers in China guarantees access to quality products that support efficient and sustainable farming practices.

Strategic Sourcing and Usage

Procuring 3-Chloro-4-fluorotoluene involves considering its packaging, typically in 25kg drums, and ensuring proper storage conditions, such as keeping it in a cool, dry, and well-ventilated place away from ignition sources. Its role as a flammable liquid necessitates careful attention to safety guidelines. The strategic sourcing of this intermediate from China offers a competitive advantage, combining quality manufacturing with cost-effectiveness for industrial applications.

In essence, 3-Chloro-4-fluorotoluene (CAS 1513-25-3) is a powerful tool for innovation in chemical manufacturing, particularly supporting the critical needs of the pharmaceutical and agrochemical industries. Its unique properties and accessibility make it a compound of significant industrial interest.