Fmoc-Val-OSu: Your Essential Amino Acid Building Block for Peptide Research
The advancement of peptide chemistry and proteomics research hinges on the availability of high-quality building blocks. Fmoc-Val-OSu, with its CAS number 130878-68-1, is a prime example of such an essential reagent. Widely recognized for its utility in solid-phase peptide synthesis (SPPS), this Fmoc-protected valine derivative is a favored choice for chemists aiming to construct complex and functional peptides. Many researchers opt to buy Fmoc-Val-OSu from specialized suppliers, including those based in China, known for their competitive pricing and reliable product quality.
The Fmoc protection strategy, utilized in Fmoc-Val-OSu, offers a robust method for managing the amine functionality of amino acids during peptide chain elongation. The Fmoc group is easily removed under mild basic conditions, a process that is orthogonal to the acid-labile side-chain protecting groups typically employed in SPPS. This orthogonal deprotection strategy is fundamental to achieving high yields and purity in the synthesis of even the most challenging peptide sequences.
The N-hydroxysuccinimide (NHS) ester moiety of Fmoc-Val-OSu serves as a highly reactive ester that facilitates the efficient formation of amide bonds. This activation mechanism ensures that the valine residue is readily coupled to the peptide backbone, contributing to the speed and success of the synthesis process. For researchers, this means a more streamlined workflow and greater confidence in the integrity of their synthesized peptides.
Sourcing Fmoc-Val-OSu with guaranteed high purity is critical. With a typical purity of 99% or more, confirmed by analytical techniques like HPLC, this reagent minimizes the risk of incorporating incorrect amino acids or impurities into the final peptide product. When you are looking to buy Fmoc-Val-OSu, paying close attention to the supplier's quality control measures and the availability of Certificates of Analysis (CoA) is essential. Many Chinese manufacturers have established themselves as key suppliers, offering products that meet international standards.
The chemical structure, C24H24N2O6, and its corresponding molecular weight of 436.45 g/mol, define the identity of Fmoc-Val-OSu. Understanding these specifications is part of good laboratory practice when working with chemical reagents. Whether for academic research, pharmaceutical development, or biotechnological applications, Fmoc-Val-OSu remains a foundational tool for creating the peptides that drive scientific innovation.
In essence, Fmoc-Val-OSu is an indispensable component for peptide chemists. Its high quality, efficient reactivity, and the robustness of the Fmoc protection strategy make it a preferred reagent for researchers aiming for precision and success in their peptide synthesis endeavors.
The Fmoc protection strategy, utilized in Fmoc-Val-OSu, offers a robust method for managing the amine functionality of amino acids during peptide chain elongation. The Fmoc group is easily removed under mild basic conditions, a process that is orthogonal to the acid-labile side-chain protecting groups typically employed in SPPS. This orthogonal deprotection strategy is fundamental to achieving high yields and purity in the synthesis of even the most challenging peptide sequences.
The N-hydroxysuccinimide (NHS) ester moiety of Fmoc-Val-OSu serves as a highly reactive ester that facilitates the efficient formation of amide bonds. This activation mechanism ensures that the valine residue is readily coupled to the peptide backbone, contributing to the speed and success of the synthesis process. For researchers, this means a more streamlined workflow and greater confidence in the integrity of their synthesized peptides.
Sourcing Fmoc-Val-OSu with guaranteed high purity is critical. With a typical purity of 99% or more, confirmed by analytical techniques like HPLC, this reagent minimizes the risk of incorporating incorrect amino acids or impurities into the final peptide product. When you are looking to buy Fmoc-Val-OSu, paying close attention to the supplier's quality control measures and the availability of Certificates of Analysis (CoA) is essential. Many Chinese manufacturers have established themselves as key suppliers, offering products that meet international standards.
The chemical structure, C24H24N2O6, and its corresponding molecular weight of 436.45 g/mol, define the identity of Fmoc-Val-OSu. Understanding these specifications is part of good laboratory practice when working with chemical reagents. Whether for academic research, pharmaceutical development, or biotechnological applications, Fmoc-Val-OSu remains a foundational tool for creating the peptides that drive scientific innovation.
In essence, Fmoc-Val-OSu is an indispensable component for peptide chemists. Its high quality, efficient reactivity, and the robustness of the Fmoc protection strategy make it a preferred reagent for researchers aiming for precision and success in their peptide synthesis endeavors.
Perspectives & Insights
Logic Thinker AI
“This orthogonal deprotection strategy is fundamental to achieving high yields and purity in the synthesis of even the most challenging peptide sequences.”
Molecule Spark 2025
“The N-hydroxysuccinimide (NHS) ester moiety of Fmoc-Val-OSu serves as a highly reactive ester that facilitates the efficient formation of amide bonds.”
Alpha Pioneer 01
“This activation mechanism ensures that the valine residue is readily coupled to the peptide backbone, contributing to the speed and success of the synthesis process.”