The Science Behind Fmoc-Val-OSu: Applications in Research and Development
In the dynamic landscape of scientific research and development, specialized chemical reagents are the backbone of innovation. Fmoc-Val-OSu, bearing the CAS number 130878-68-1, is one such indispensable compound, widely recognized for its critical role in peptide synthesis and its growing importance in proteomics. When researchers seek to buy Fmoc-Val-OSu, they are looking for a reagent that ensures both purity and efficiency, often finding reliable sources from manufacturers and suppliers globally, including those in China.
The primary application of Fmoc-Val-OSu lies in solid-phase peptide synthesis (SPPS). The Fmoc (9-fluorenylmethyloxycarbonyl) protection strategy is a cornerstone of modern SPPS, allowing for the stepwise assembly of amino acids onto a solid support. Fmoc-Val-OSu utilizes this strategy, providing the valine amino acid with its amine group protected by the Fmoc moiety. This protection is readily cleaved under mild basic conditions, making it compatible with a wide range of other protecting groups and synthetic conditions. Furthermore, the N-hydroxysuccinimide (NHS) ester activation of the valine carboxyl group in Fmoc-Val-OSu ensures efficient coupling, leading to higher yields and improved purity of the synthesized peptides.
The significance of sourcing high-purity Fmoc-Val-OSu cannot be overstated. Purity levels, typically exceeding 99% as confirmed by HPLC, are crucial for preventing the incorporation of unwanted amino acids or byproducts into the peptide chain. This high purity is essential for the reliable functioning of synthesized peptides in biological assays, drug discovery programs, and proteomic studies. Researchers often depend on Certificates of Analysis (CoA) from suppliers to verify the quality and specifications of Fmoc-Val-OSu, ensuring consistency in their experimental results.
The chemical identity of Fmoc-Val-OSu is defined by its molecular formula C24H24N2O6 and a molecular weight of approximately 436.45 g/mol. These specifications are critical for accurate stoichiometric calculations and successful experimental design. For laboratories requiring larger quantities, exploring suppliers in China can offer a strategic advantage due to competitive pricing and established production capabilities.
In conclusion, Fmoc-Val-OSu is a fundamental reagent that empowers advancements in peptide chemistry and proteomics. Its application in SPPS, coupled with its high purity and efficient coupling capabilities, makes it a preferred choice for researchers worldwide. Ensuring access to reliable Fmoc-Val-OSu suppliers is a key step in achieving successful and impactful research outcomes.
The primary application of Fmoc-Val-OSu lies in solid-phase peptide synthesis (SPPS). The Fmoc (9-fluorenylmethyloxycarbonyl) protection strategy is a cornerstone of modern SPPS, allowing for the stepwise assembly of amino acids onto a solid support. Fmoc-Val-OSu utilizes this strategy, providing the valine amino acid with its amine group protected by the Fmoc moiety. This protection is readily cleaved under mild basic conditions, making it compatible with a wide range of other protecting groups and synthetic conditions. Furthermore, the N-hydroxysuccinimide (NHS) ester activation of the valine carboxyl group in Fmoc-Val-OSu ensures efficient coupling, leading to higher yields and improved purity of the synthesized peptides.
The significance of sourcing high-purity Fmoc-Val-OSu cannot be overstated. Purity levels, typically exceeding 99% as confirmed by HPLC, are crucial for preventing the incorporation of unwanted amino acids or byproducts into the peptide chain. This high purity is essential for the reliable functioning of synthesized peptides in biological assays, drug discovery programs, and proteomic studies. Researchers often depend on Certificates of Analysis (CoA) from suppliers to verify the quality and specifications of Fmoc-Val-OSu, ensuring consistency in their experimental results.
The chemical identity of Fmoc-Val-OSu is defined by its molecular formula C24H24N2O6 and a molecular weight of approximately 436.45 g/mol. These specifications are critical for accurate stoichiometric calculations and successful experimental design. For laboratories requiring larger quantities, exploring suppliers in China can offer a strategic advantage due to competitive pricing and established production capabilities.
In conclusion, Fmoc-Val-OSu is a fundamental reagent that empowers advancements in peptide chemistry and proteomics. Its application in SPPS, coupled with its high purity and efficient coupling capabilities, makes it a preferred choice for researchers worldwide. Ensuring access to reliable Fmoc-Val-OSu suppliers is a key step in achieving successful and impactful research outcomes.
Perspectives & Insights
Alpha Spark Labs
“Purity levels, typically exceeding 99% as confirmed by HPLC, are crucial for preventing the incorporation of unwanted amino acids or byproducts into the peptide chain.”
Future Pioneer 88
“This high purity is essential for the reliable functioning of synthesized peptides in biological assays, drug discovery programs, and proteomic studies.”
Core Explorer Pro
“Researchers often depend on Certificates of Analysis (CoA) from suppliers to verify the quality and specifications of Fmoc-Val-OSu, ensuring consistency in their experimental results.”