For researchers and chemical engineers, understanding the detailed specifications of a chemical compound is the first step towards successful application. 1-Benzyl-4-hydroxypiperidine (CAS 4727-72-4) is a compound that warrants close examination due to its significant utility, particularly as a pharmaceutical intermediate. This article provides a comprehensive overview of its chemical and physical properties and guides buyers on how to effectively source it from reputable suppliers.

Detailed Chemical and Physical Properties

1-Benzyl-4-hydroxypiperidine, with the molecular formula C12H17NO and a molecular weight of approximately 191.27 g/mol, is recognized for its distinct structure and characteristics. It typically presents as a white to off-white crystalline powder, with a melting point range of 61-63°C. Purity is a critical specification, with most commercial grades offering ≥98.0% purity, often verified by techniques such as GC. The presence of a hydroxyl group and a tertiary amine makes it a versatile reactant in various organic transformations. These properties are crucial for its role as a building block in the synthesis of complex organic molecules, including active pharmaceutical ingredients (APIs).

Applications and Industrial Relevance

The primary industrial relevance of 1-Benzyl-4-hydroxypiperidine lies in its application as a key pharmaceutical intermediate. It is integral to the synthesis of various drugs, including those targeting pain management and neurological disorders. Its specific structural features allow medicinal chemists to design and create novel compounds with enhanced therapeutic properties. Beyond pharmaceuticals, its utility extends to general organic synthesis, where it serves as a valuable starting material or intermediate for creating diverse chemical entities. For businesses needing to purchase this compound, understanding these applications helps in defining their quality requirements.

Finding Reliable Suppliers and Getting Quotes

Securing a consistent and high-quality supply of 1-Benzyl-4-hydroxypiperidine is essential for uninterrupted research and production. Potential buyers should look for manufacturers and suppliers who can provide consistent product quality, accurate specifications, and reliable delivery. Sourcing from established chemical suppliers, particularly those based in major chemical manufacturing regions like China, often yields competitive pricing and ensures a steady supply. When you are ready to buy, reaching out to multiple suppliers for quotes based on your required purity and quantity is a recommended strategy. Verify their credentials and request batch-specific Certificates of Analysis to ensure you are obtaining a product that meets your stringent needs.