In the intricate field of chemical synthesis, the availability of high-quality intermediates is fundamental to achieving successful outcomes. 1-Phenylpiperazine, identified by its CAS number 92-54-6, stands as a significant compound, valued for its versatility and critical applications across various industrial sectors, most notably in pharmaceuticals and fine chemicals. For professionals in these domains, understanding its properties and procurement channels is essential.

1-Phenylpiperazine (C10H14N2, MW: 162.23) is a chemical intermediate that typically appears as a colorless to light yellow liquid. Its physical characteristics, such as a boiling point of 286°C and a melting point of 18.8°C, along with a purity of ≥99.0%, make it a preferred choice for many synthesis pathways. These attributes are vital for applications requiring precise chemical reactions and consistent product quality.

The primary role of 1-Phenylpiperazine is as a chemical intermediate. In the pharmaceutical industry, it serves as a crucial building block for synthesizing Active Pharmaceutical Ingredients (APIs), such as Levodropropizine. Furthermore, it is recognized as an impurity reference standard, which is indispensable for quality assurance and control in drug manufacturing. Companies looking to buy 1-Phenylpiperazine for these stringent applications must ensure they source from manufacturers with robust quality management systems.

Beyond its pharmaceutical relevance, 1-Phenylpiperazine is widely utilized in general organic synthesis. Its unique structure allows chemists to create a diverse range of complex organic molecules, contributing to advancements in material science and chemical research. As such, it is a sought-after intermediate for custom synthesis projects and academic research. Identifying reliable suppliers that can offer competitive pricing and consistent product availability is key for such endeavors.

For procurement managers and R&D scientists, understanding the sourcing landscape is paramount. Many reliable manufacturers and suppliers are located in China, offering competitive pricing and efficient logistics. When considering a purchase, it is advisable to request detailed product specifications, safety data sheets (SDS), and certificates of analysis (CoA) to ensure the intermediate meets all necessary requirements. Exploring options from different suppliers can also provide valuable insights into market pricing and lead times.

In essence, 1-Phenylpiperazine (CAS: 92-54-6) is a critical intermediate that fuels innovation in the pharmaceutical and chemical synthesis industries. By focusing on sourcing from reputable manufacturers and suppliers, ensuring high purity, and understanding its application scope, businesses can effectively integrate this versatile compound into their product development and manufacturing processes.