1-Phenylpiperazine, identified by its CAS number 92-54-6, is a significant chemical compound with a range of applications, particularly in the pharmaceutical and fine chemical industries. For professionals engaged in R&D or procurement, a comprehensive understanding of its properties and uses is essential. This article delves into the physical and chemical characteristics of 1-Phenylpiperazine and its vital roles, offering insights for those looking to buy this intermediate.

Chemically known as 1-Phenylpiperazine or N-Phenylpiperazine, this compound (C10H14N2, MW: 162.23) is a derivative of piperazine. Its physical appearance is typically described as a colorless to light yellow liquid. Key physical parameters include a boiling point of 286°C and a melting point of 18.8°C, with a density of 1.062 g/mL at 25°C. Its refractive index is n20/D 1.588. These properties are crucial for chemists and engineers involved in its handling, storage, and integration into synthesis processes.

The primary utility of 1-Phenylpiperazine lies in its function as a chemical intermediate. It plays a crucial role in the synthesis of pharmaceutical compounds. For instance, it is recognized as an impurity standard and a synthetic precursor for Levodropropizine, an active pharmaceutical ingredient used in cough suppressants. This application highlights the demand for high-purity 1-Phenylpiperazine from reliable manufacturers. Researchers often need to purchase this compound for analytical purposes, ensuring the quality control of pharmaceutical products.

Furthermore, 1-Phenylpiperazine is a valuable building block in broader organic synthesis. Its reactive nature makes it suitable for constructing complex organic molecules, which can lead to the development of new materials or compounds with specific functionalities. For companies seeking to innovate, securing a consistent supply of this intermediate from a trusted supplier is a strategic imperative. Understanding the global market and identifying reliable suppliers, particularly in regions like China, can also influence price and availability.

When considering the purchase of 1-Phenylpiperazine, it’s important to note its specifications, such as a minimum purity of 99.0%. Additionally, moisture content and impurity levels are critical parameters that manufacturers must control. For procurement managers, requesting detailed specifications and Certificates of Analysis (CoA) from potential suppliers is a standard practice to ensure that the material meets the required standards for their intended applications. Exploring different suppliers can help in finding competitive pricing for bulk orders.

In summary, 1-Phenylpiperazine (CAS: 92-54-6) is a compound of significant industrial importance. Its well-defined physical and chemical properties, coupled with its critical role as a pharmaceutical intermediate and a versatile organic synthesis building block, make it a valuable commodity. By understanding its characteristics and engaging with quality-focused manufacturers and suppliers, businesses can effectively source this essential chemical intermediate.