The pharmaceutical industry relies heavily on a consistent supply of high-quality chemical intermediates to develop and manufacture life-saving and life-enhancing medications. Among these crucial compounds, 1-Phenylpiperazine (CAS: 92-54-6) plays a significant role, particularly as a key intermediate and reference standard in the synthesis of various pharmaceuticals.

1-Phenylpiperazine, with the chemical formula C10H14N2 and a molecular weight of 162.23, is a derivative of piperazine. It is typically supplied as a colorless to light yellow liquid, possessing a boiling point of 286°C and a melting point of 18.8°C. Its chemical structure, featuring a phenyl group attached to the piperazine ring, lends itself to diverse synthetic applications. For professionals in pharmaceutical R&D and manufacturing, understanding its purity specifications, usually 99.0% or higher, is paramount.

The primary utility of 1-Phenylpiperazine within the pharmaceutical sector is its function as a critical intermediate in the synthesis of Active Pharmaceutical Ingredients (APIs). A notable example is its use in the production of Levodropropizine, an antitussive agent. In this context, 1-Phenylpiperazine is not only a direct building block but also serves as an important reference standard for identifying and quantifying potential impurities, thereby ensuring the purity and safety of the final drug product. This makes reliable sourcing from reputable manufacturers essential for compliance and quality control.

For organizations looking to buy 1-Phenylpiperazine, identifying trusted manufacturers and suppliers is a key step. Global sourcing, particularly from China, offers opportunities to access high-purity materials at competitive prices. Procurement managers and scientists should prioritize suppliers who provide comprehensive documentation, including Certificates of Analysis (CoA), and maintain a stable supply chain. Inquiring about bulk purchase options can further optimize cost-effectiveness.

Beyond its direct role in API synthesis, 1-Phenylpiperazine is also a valuable compound in broader organic chemistry, facilitating the creation of complex molecules for research purposes. Its versatility makes it a staple in many chemical laboratories and custom synthesis operations.

In conclusion, 1-Phenylpiperazine (CAS: 92-54-6) is an indispensable intermediate for the pharmaceutical industry. Its critical function in API synthesis and its importance as an impurity standard underscore the need for high-purity materials. By partnering with reliable manufacturers and suppliers, pharmaceutical companies can ensure a consistent and quality-assured supply, driving innovation and maintaining the highest standards in drug development and production.