The pharmaceutical industry's quest for novel therapeutics is powered by a sophisticated understanding and utilization of chemical building blocks. 2-Amidinopyrimidine Hydrochloride (CAS: 138588-40-6) stands out as a critical intermediate, instrumental in the synthesis of various advanced pharmaceutical compounds. This article explores its importance, applications, and why sourcing from reliable manufacturers is vital for innovation.

The Chemical Identity and Significance

2-Amidinopyrimidine Hydrochloride, identifiable by its CAS number 138588-40-6, is characterized as a grey white powder. Its molecular structure, featuring a pyrimidine ring functionalized with an amidine group and a hydrochloride salt, provides a versatile platform for organic synthesis. With a purity level typically exceeding 98%, it is highly valued in the pharmaceutical sector for its contribution to creating complex APIs. A prime example of its application is in the synthesis of Bosentan, a medication addressing pulmonary arterial hypertension, highlighting its role in developing treatments for serious medical conditions.

Why is it a Crucial Building Block?

As a building block, 2-Amidinopyrimidine Hydrochloride offers several advantages for pharmaceutical R&D and manufacturing:

  • Synthetic Versatility: The pyrimidine core and reactive amidine group allow for diverse chemical modifications, enabling the creation of a wide range of novel drug candidates.
  • Efficiency in Synthesis: Its well-defined structure and high purity contribute to more efficient and predictable synthesis routes, reducing reaction steps and potential by-products.
  • Enabling Complex Molecule Formation: It serves as a foundational element for constructing intricate molecular architectures required for targeted drug action.
  • Quality Cornerstone: When you buy 2-Amidinopyrimidine Hydrochloride from a reputable manufacturer, you are investing in the quality and reliability of your final API. This directly impacts the drug's efficacy and safety profile.

Sourcing and Partnership Considerations

For pharmaceutical companies, securing a consistent supply of high-quality 2-Amidinopyrimidine Hydrochloride is essential. This involves:

  • Partnering with Experienced Suppliers: Engaging with a specialized pharmaceutical intermediate supplier, such as NINGBO INNO PHARMCHEM CO.,LTD., ensures access to expertise and quality products. We are a trusted 2-Amidinopyrimidine Hydrochloride supplier in China with a strong commitment to quality.
  • Understanding the Market Price: While seeking competitive pricing for pyrimidine-2-carboximidamide hydrochloride, it's vital to balance cost with the supplier's reputation, quality certifications, and the availability of technical documentation.
  • Ensuring Supply Chain Integrity: A stable and robust supply chain is crucial for uninterrupted R&D and production schedules.

NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to empowering pharmaceutical innovation by providing exceptional 2-Amidinopyrimidine Hydrochloride. We invite you to connect with us to discuss your needs for this vital building block and explore how our commitment to quality and service can benefit your projects. Discover the difference a reliable supplier makes.