The pharmaceutical industry relies heavily on a diverse array of chemical intermediates to synthesize life-saving drugs. Among these, heterocyclic compounds like 2-Amidinopyrimidine Hydrochloride (CAS: 138588-40-6) are indispensable. This article delves into the properties, applications, and market significance of this compound, offering insights for professionals involved in pharmaceutical R&D and manufacturing.

Understanding 2-Amidinopyrimidine Hydrochloride

2-Amidinopyrimidine Hydrochloride, identified by its CAS registry number 138588-40-6, is a chemical compound characterized by its grey white powder appearance. Its molecular formula is C5H6N4.HCl, and it has a molecular weight of approximately 158.59. A key attribute for its use in pharmaceutical synthesis is its high purity, typically maintained at or above 98% by reputable manufacturers. This compound is a derivative of pyrimidine, a fundamental heterocyclic aromatic organic compound, making it a valuable building block in medicinal chemistry.

Applications in Pharmaceutical Synthesis

The primary application of 2-Amidinopyrimidine Hydrochloride is as a crucial intermediate in the synthesis of Active Pharmaceutical Ingredients (APIs). Its most notable use is in the production of Bosentan, a dual endothelin receptor antagonist used in the treatment of pulmonary arterial hypertension. The specific structure of 2-Amidinopyrimidine Hydrochloride allows for efficient incorporation into complex synthetic routes, contributing to the formation of the target drug molecule. For researchers and companies looking to buy 2-Amidinopyrimidine Hydrochloride for Bosentan synthesis or other novel drug development projects, securing a reliable source is paramount.

Market Relevance and Supplier Selection

The demand for high-quality pharmaceutical intermediates like 2-Amidinopyrimidine Hydrochloride is directly tied to the growth and innovation within the pharmaceutical sector. When sourcing this compound, professionals should consider:

  • Quality Assurance: Partnering with a 2-Amidinopyrimidine Hydrochloride manufacturer that adheres to strict quality control measures is essential. This includes verifying purity levels and ensuring batch-to-batch consistency.
  • Supply Chain Stability: The ability of a pharmaceutical intermediate supplier to provide a stable and continuous supply is critical for uninterrupted production. Experience in international trade and robust logistics are key indicators.
  • Competitive Pricing: While quality is paramount, understanding the market price of pyrimidine-2-carboximidamide hydrochloride from various reliable suppliers can help optimize R&D and manufacturing budgets.
  • Technical Support: Suppliers who offer technical data, COAs, and responsive customer service can significantly ease the procurement process for R&D teams.

NINGBO INNO PHARMCHEM CO.,LTD. is a dedicated supplier of 2-Amidinopyrimidine Hydrochloride, offering high-purity material backed by comprehensive quality assurance and expert support. We are committed to meeting the needs of the pharmaceutical industry by providing reliable sourcing solutions. Contact us today to discuss your requirements for this vital intermediate.