(4R)-4-hydroxypyrrolidin-2-one: A Versatile Chiral Building Block for Drug Discovery
The landscape of pharmaceutical development is constantly evolving, driven by the need for more effective and safer therapeutic agents. Central to this progress is the availability of versatile chiral building blocks, compounds that possess specific three-dimensional arrangements crucial for biological activity. Among these, (4R)-4-hydroxypyrrolidin-2-one (CAS: 22677-21-0) emerges as a particularly valuable intermediate. While its primary association is with the synthesis of Oxiracetam, this chiral pyrrolidinone offers a much broader utility for drug discovery and fine chemical synthesis. If you are looking to buy (4R)-4-hydroxypyrrolidin-2-one, understanding its diverse applications can significantly enhance your research and development efforts.
As an established manufacturer and supplier based in China, we recognize the importance of this compound. (4R)-4-hydroxypyrrolidin-2-one is more than just an intermediate for a single nootropic; its inherent chirality and functional groups make it an ideal starting material for a wide array of complex molecules. Its hydroxyl and lactam functionalities can be readily modified, allowing chemists to construct diverse molecular architectures. This makes it an attractive component for developing single-isomer drugs across various therapeutic classes, including those targeting antitumor, anesthetic, antipasmodic, anti-inflammatory, and even anti-HIV applications.
The specific optical activity and high purity of our (4R)-4-hydroxypyrrolidin-2-one are critical. In drug discovery, even minor variations in stereochemistry can lead to significant differences in a drug’s pharmacological profile, affecting its potency, selectivity, and potential for side effects. Therefore, sourcing this intermediate from a reliable supplier that guarantees consistent quality is essential. Researchers and developers often inquire about the price for cas 22677-21-0 to budget for their projects, and we are committed to providing competitive pricing for high-grade material.
The versatility of (4R)-4-hydroxypyrrolidin-2-one extends to its use in fine chemical synthesis, where it can be incorporated into novel materials or as a key fragment in combinatorial chemistry libraries. Its structural motif is a common feature in many biologically active natural products and synthetic molecules, further highlighting its importance as a versatile building block. For companies involved in advanced drug discovery, having access to such foundational chiral intermediates is a significant advantage, enabling faster exploration of chemical space and more efficient synthesis of promising drug candidates.
In summary, (4R)-4-hydroxypyrrolidin-2-one is a compound of considerable strategic value in the pharmaceutical and chemical industries. Its utility extends far beyond its role in Oxiracetam synthesis, offering significant potential for developing targeted therapies and novel fine chemicals. By sourcing this key intermediate from a trusted manufacturer, you can ensure the quality and efficiency needed to drive your drug discovery initiatives forward.
Perspectives & Insights
Data Seeker X
“For companies involved in advanced drug discovery, having access to such foundational chiral intermediates is a significant advantage, enabling faster exploration of chemical space and more efficient synthesis of promising drug candidates.”
Chem Reader AI
“In summary, (4R)-4-hydroxypyrrolidin-2-one is a compound of considerable strategic value in the pharmaceutical and chemical industries.”
Agile Vision 2025
“Its utility extends far beyond its role in Oxiracetam synthesis, offering significant potential for developing targeted therapies and novel fine chemicals.”