In the complex landscape of pharmaceutical development and manufacturing, specific chemical intermediates serve as foundational elements for creating life-saving medications. 6-Chlorouracil, identified by its CAS number 4270-27-3, is one such compound, playing a vital role as a pharmaceutical intermediate in the synthesis of various active pharmaceutical ingredients (APIs).

Chemical Profile and Properties

6-Chlorouracil is an organic compound characterized by its molecular formula C4H3ClN2O2 and a molecular weight of 146.53 g/mol. It typically presents as a white to off-white crystalline powder, and its purity is a crucial specification, often required at 99% or higher for pharmaceutical applications. This high level of purity is essential to ensure the efficacy and safety of the final drug product and to maintain consistency in manufacturing processes.

Key Applications in the Pharmaceutical Industry

The primary significance of 6-Chlorouracil lies in its function as a pharmaceutical intermediate. It serves as a key building block in the synthetic pathways for various drug molecules. A prominent example is its use in the production of alogliptin, a medication prescribed for managing type 2 diabetes. The reactive chlorine atom on the uracil ring allows for facile derivatization, enabling chemists to construct the intricate molecular structures necessary for therapeutic activity. Beyond specific API synthesis, 6-Chlorouracil also finds utility as a biochemical reagent in research settings, aiding in the study of enzymatic processes and biological pathways.

Sourcing 6-Chlorouracil: Manufacturer and Supplier Considerations

For pharmaceutical companies, identifying a reliable 6-chlorouracil manufacturer is paramount. When you intend to purchase 6-chlorouracil, it is vital to select suppliers who can guarantee consistent quality, high purity (99%), and timely delivery. Sourcing from established chemical providers, especially those with a strong presence in manufacturing hubs like China, can offer both cost advantages and large-scale production capabilities. Understanding the full product specifications, including CAS 4270-27-3, and obtaining necessary documentation like Certificates of Analysis are critical steps in the procurement process.

Ensuring a steady and high-quality supply of essential intermediates like 6-Chlorouracil is foundational for successful pharmaceutical production. We are a dedicated 6-chlorouracil supplier committed to meeting the stringent demands of the pharmaceutical sector. We invite you to get a quote to learn more about our products and services and how we can support your manufacturing needs.