In the realm of pharmaceutical development, the precise synthesis of complex molecules is a hallmark of success. Central to many of these synthetic pathways are intermediate compounds that act as crucial building blocks. 7-Chloro-2-methylquinoline, bearing the CAS number 4965-33-7, stands out as a cornerstone intermediate, particularly within the pharmaceutical industry. Its unique chemical structure and reactivity make it indispensable for the creation of various therapeutic agents.

The Chemical Identity of 7-Chloro-2-methylquinoline

Chemically designated as 7-Chloro-2-methylquinoline, or often referred to by its synonym 7-Chloroquinaldine, this compound is a derivative of quinoline. Its molecular formula is C10H8ClN, with a molecular weight of approximately 177.63 g/mol. Typically presented as a crystalline powder, its color ranges from white to a light beige, and it possesses a melting point in the range of 74-78°C. This physical form and melting range are important characteristics for its handling and processing in synthetic chemistry. As a prominent supplier, we ensure this compound is manufactured to meet high purity standards, often above 99%, which is critical for its intended applications.

Key Role in Pharmaceutical Manufacturing

The significance of 7-Chloro-2-methylquinoline is most evident in its application as a critical intermediate in the synthesis of Montelukast Sodium Salt. Montelukast is a widely prescribed medication used to manage asthma and allergic rhinitis, conditions affecting millions globally. The synthetic route to Montelukast involves several steps, and 7-Chloro-2-methylquinoline serves as an essential starting material, providing the core quinoline structure that is further elaborated upon.

Beyond its role in Montelukast synthesis, 7-Chloro-2-methylquinoline's structural features make it valuable for the development of other quinoline-based compounds. The quinoline moiety is a privileged scaffold in medicinal chemistry, found in drugs used to treat a variety of diseases, including antimalarials, antimicrobials, and even some anti-cancer agents. Researchers and pharmaceutical companies actively seek reliable sources to purchase this versatile intermediate to explore new therapeutic avenues and optimize existing drug synthesis processes.

Ensuring Quality and Reliability

For any pharmaceutical manufacturer or research institution, securing a consistent and high-quality supply of intermediates like 7-Chloro-2-methylquinoline is paramount. When seeking to buy this compound, it is crucial to partner with reputable suppliers who can guarantee purity, provide detailed analytical documentation (such as CoAs), and maintain robust production capacities. Companies like NINGBO INNO PHARMCHEM CO.,LTD. specialize in providing pharmaceutical-grade intermediates, ensuring that the materials meet the rigorous demands of drug synthesis.

In conclusion, 7-Chloro-2-methylquinoline is a vital chemical intermediate that underpins the production of important pharmaceuticals. Its consistent quality and availability are essential for the pharmaceutical industry, supporting the ongoing development and accessibility of life-improving medications.