The journey from raw chemical to life-saving medication is complex, with each intermediate playing a pivotal role. For Indacaterol, a critical treatment for COPD, 8-Benzyloxy-5-(2-bromoacetyl)-2-hydroxyquinoline (CAS 100331-89-3) stands out as a crucial chemical link. This article delves into the properties, applications, and market availability of this important pharmaceutical intermediate, aimed at R&D scientists, formulators, and procurement specialists.

Chemical Profile of CAS 100331-89-3

Chemically known as 8-Benzyloxy-5-(2-bromoacetyl)-2-hydroxyquinoline, this compound boasts a molecular formula of C18H14BrNO3 and a molecular weight of 372.21. Its typical appearance as an off-white powder, coupled with a high assay purity of ≥98.0%, makes it an ideal candidate for sophisticated pharmaceutical synthesis. The presence of the bromoacetyl group and the quinoline core structure are key functional elements that facilitate its transformation into the final Indacaterol molecule. Understanding these chemical characteristics is vital for process chemists aiming to optimize reaction yields and purity.

The Indispensable Role in Indacaterol Production

Indacaterol, a long-acting beta-adrenoceptor agonist, is essential for managing the symptoms of COPD. The synthesis of Indacaterol involves a series of precise chemical reactions, and 8-Benzyloxy-5-(2-bromoacetyl)-2-hydroxyquinoline is a non-negotiable precursor. Its role is to introduce specific structural motifs that are later modified to achieve the final therapeutic compound. Pharmaceutical manufacturers rely heavily on a consistent and high-quality supply of this intermediate to ensure uninterrupted production of Indacaterol Maleate, the commercially available salt form.

Procurement and Supply Chain Excellence

For businesses looking to buy 8-Benzyloxy-5-(2-bromoacetyl)-2-hydroxyquinoline, partnering with a reputable manufacturer and supplier is paramount. As a dedicated supplier based in China, we are committed to delivering excellence in both product quality and service. Our production processes are optimized to ensure high purity and batch-to-batch consistency. We understand the importance of a robust supply chain for API intermediates, and we work diligently to provide timely deliveries and comprehensive support to our clients worldwide.

When considering a purchase, it’s beneficial to engage with suppliers who can offer competitive pricing for bulk orders and provide detailed specifications and safety data. Our team is readily available to answer inquiries regarding pricing, availability, and technical specifications, ensuring a smooth procurement process.

Future Outlook and Applications

As the global demand for effective respiratory treatments continues to grow, so does the importance of key intermediates like 8-Benzyloxy-5-(2-bromoacetyl)-2-hydroxyquinoline. Pharmaceutical research may also uncover new applications or improved synthesis routes involving this versatile chemical. For companies involved in API manufacturing and pharmaceutical R&D, maintaining a strong relationship with reliable suppliers of such intermediates is a strategic advantage. We invite you to explore our capabilities as a leading manufacturer and supplier and discover how we can meet your needs for high-quality pharmaceutical intermediates.