The quest for novel and effective pharmaceuticals often leads researchers to complex heterocyclic compounds that form the backbone of many advanced therapeutic agents. Among these, pyrrolo[2,3-b]pyridine derivatives have gained significant attention due to their versatile biological activities and applications in drug discovery. One such critical molecule we manufacture is N-(3-(5-bromo-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide, known by its CAS number 918504-27-5.

This compound is particularly recognized for its indispensable role as an intermediate in the synthesis of Vemurafenib, a targeted therapy used in the treatment of certain cancers. As a specialized manufacturer of advanced pharmaceutical intermediates, our production of this molecule adheres to stringent quality protocols, ensuring a high purity of ≥98.0%. This commitment is crucial for supporting the complex multi-step syntheses required in modern drug development.

The chemical structure of N-(3-(5-bromo-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide, defined by its formula C17H14BrF2N3O3S and a molecular weight of 458.27700, presents significant synthetic challenges that we have mastered. It features a brominated pyrrolo[2,3-b]pyridine core, which is a common motif in biologically active compounds. Its availability as a white to yellow crystalline powder facilitates its use in various synthetic procedures, making it a valuable commodity for R&D departments and manufacturing facilities.

For pharmaceutical companies, the reliable sourcing of such advanced intermediates is a strategic imperative. We serve as a dedicated manufacturer and supplier, offering this critical building block from our facilities in China. Our capacity to produce this intermediate in scalable quantities, typically in 25 kg drums, allows us to meet the diverse needs of our clients, from early-stage research to commercial production. When you need to buy this specific pyrrolo[2,3-b]pyridine derivative, partnering with us ensures a stable and high-quality supply.

The development of new drugs requires a robust ecosystem of chemical suppliers who can provide the essential molecular components. Our focus on advanced intermediates like CAS 918504-27-5 positions us as a key enabler in the pharmaceutical value chain. We are committed to supporting the groundbreaking work of researchers and manufacturers by providing them with the highest quality materials. If your drug development program requires this vital intermediate, we encourage you to contact us to secure your supply and explore our custom synthesis capabilities.