The intricate machinery of the mitochondrion is central to cellular life, governing energy production and playing a key role in cell fate. For researchers dedicated to unraveling these complex processes, Carboxyatractyloside (CAS 35988-42-2) emerges as an indispensable tool. This article highlights its significance in investigating mitochondrial function and provides guidance for researchers looking to acquire this specialized biochemical.

Carboxyatractyloside's primary scientific contribution lies in its potent and specific inhibition of the mitochondrial ADP/ATP translocase. This crucial protein complex facilitates the exchange of adenosine diphosphate (ADP) and adenosine triphosphate (ATP) across the inner mitochondrial membrane, a fundamental step in cellular energy generation. By blocking this exchange with Carboxyatractyloside, researchers can precisely dissect the impact of impaired ATP production on cellular metabolism, respiration, and overall bioenergetic status. This makes it invaluable for studying conditions characterized by mitochondrial dysfunction.

Moreover, C-ATR is known to induce mitochondrial membrane permeabilization, a critical trigger for apoptosis, or programmed cell death. This property allows researchers to experimentally induce cell death pathways and investigate the underlying molecular mechanisms. Understanding how mitochondrial integrity is compromised in various diseases, such as cancer or neurodegenerative disorders, is a key area where Carboxyatractyloside proves its worth.

For scientists seeking to buy Carboxyatractyloside, partnering with reliable manufacturers and suppliers is paramount to ensure the purity and consistency required for accurate experimental outcomes. China has become a significant source for high-quality research chemicals, offering competitive pricing for compounds like C-ATR. Researchers should always inquire about product specifications, including purity (typically >95%) and CAS number (35988-42-2), when requesting quotes.

The physical characteristics of Carboxyatractyloside are generally described as a white solid. When considering procurement, it is advisable to seek out suppliers who provide comprehensive documentation, such as a Certificate of Analysis, to verify the compound's quality. Furthermore, understanding the available quantities and potential for bulk discounts can be beneficial for institutions with ongoing research programs. The ability to secure a stable and cost-effective supply of this critical inhibitor is essential for driving progress in mitochondrial research.

In conclusion, Carboxyatractyloside (CAS 35988-42-2) is a highly valuable research chemical for anyone studying mitochondrial function and apoptosis. By diligently sourcing from reputable suppliers, researchers can harness the power of this potent inhibitor to gain deeper insights into cellular life and disease, ultimately contributing to advancements in human health.