In the realm of biochemical research, understanding the fundamental processes of cellular energy production and programmed cell death is key to unlocking new therapeutic strategies. Carboxyatractyloside (CAS 35988-42-2), often referred to as C-ATR, plays a vital role in this research landscape. This article delves into the applications of Carboxyatractyloside and guides researchers on how to acquire this essential biochemical compound.

The primary scientific utility of Carboxyatractyloside lies in its function as a specific inhibitor of the mitochondrial ADP/ATP translocase. This critical enzyme is responsible for the exchange of ADP and ATP across the inner mitochondrial membrane, a process fundamental to cellular energy homeostasis. By inhibiting this translocase, researchers can investigate the impact of disrupted energy production on various cellular functions, including cellular respiration, metabolic pathways, and overall cell viability. This makes C-ATR an invaluable tool for studying conditions where mitochondrial dysfunction is implicated.

Furthermore, Carboxyatractyloside is recognized for its ability to induce mitochondrial membrane permeabilization. This effect is a critical step in the activation of the intrinsic apoptotic pathway, a tightly regulated process of programmed cell death. Researchers studying apoptosis, cancer, and various degenerative diseases utilize C-ATR to experimentally trigger and observe these complex cellular events. This allows for a deeper understanding of the molecular mechanisms underlying cell death and survival.

For scientists looking to buy Carboxyatractyloside for their laboratory needs, it is paramount to source from reliable suppliers who can guarantee high purity and consistency. China has become a significant global producer of fine chemicals, offering a wide array of research compounds, including C-ATR. When inquiring about price, it is common to find competitive rates, especially when purchasing in larger research quantities. Procurement managers should always request a quote for the specific amount needed.

Key identifiers for Carboxyatractyloside include its CAS number (35988-42-2), its chemical formula (C31H46O18S2), and its typical appearance as a white solid. Purity levels of >95% are generally expected for research applications. When sourcing this compound, especially for sensitive experiments, partnering with established manufacturers that adhere to strict quality control standards is crucial. This ensures the accuracy and reproducibility of research findings.

In summary, Carboxyatractyloside (CAS 35988-42-2) is an essential biochemical for researchers investigating cellular energy metabolism and apoptosis. By understanding its applications and knowing where to procure high-quality material from dependable suppliers, scientists can effectively utilize this compound to advance their research objectives and contribute to the broader scientific community.