In the intricate world of cellular biology, understanding energy production and cell death pathways is paramount. Carboxyatractyloside (CAS 35988-42-2) emerges as a critical compound for researchers delving into these complex processes. This article aims to shed light on its properties, applications, and how procurement professionals can effectively source this vital research chemical.

Carboxyatractyloside, often abbreviated as C-ATR, is a natural heteroglucoside known for its potent inhibitory effect on the mitochondrial ADP/ATP translocase (ANT). This translocase is fundamental to cellular energy metabolism, facilitating the exchange of adenine nucleotides across the inner mitochondrial membrane. By inhibiting ANT, Carboxyatractyloside effectively disrupts ATP synthesis, making it an invaluable tool for studying cellular respiration and energy homeostasis.

Beyond its role in energy metabolism, C-ATR is also recognized as a proapoptotic ligand. It induces pore formation in the ANT, leading to the permeabilization of the mitochondrial membrane. This disruption is a key step in initiating programmed cell death, or apoptosis. Therefore, researchers investigating cell death mechanisms, or developing therapeutic strategies related to apoptosis, find Carboxyatractyloside to be an indispensable reagent.

From a procurement perspective, sourcing high-quality Carboxyatractyloside is crucial for ensuring the reliability and reproducibility of experimental results. When looking to buy this compound, it is essential to partner with reputable manufacturers and suppliers. China has emerged as a significant hub for the production of fine chemicals, offering competitive pricing and a wide range of options for this specific molecule. Procurement managers seeking to secure a stable supply can benefit greatly from exploring the offerings of Chinese chemical companies.

Key technical specifications to consider when purchasing Carboxyatractyloside include its purity, typically above 95%, and its form, which is generally a white solid. Its CAS number, 35988-42-2, is the primary identifier for accurate sourcing. When inquiring about price, be sure to specify the required quantity, as bulk orders often come with favorable discounts. For instance, requesting a quote for 1g or larger quantities can lead to significant cost savings for ongoing research projects.

In conclusion, Carboxyatractyloside is a powerful research chemical with significant implications for understanding fundamental biological processes. By leveraging the capabilities of global suppliers, particularly those in China, researchers and procurement specialists can ensure access to this critical compound, driving forward advancements in cellular biology, biochemistry, and pharmaceutical research. Always remember to confirm the intended use is for research purposes only, as is standard for such specialized reagents.