In the realm of pharmaceutical chemical synthesis, the precise structure and quality of intermediates are fundamental to producing safe and effective medicines. One such crucial compound is 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid, an essential precursor in the production of important antibiotics. This article aims to provide a comprehensive overview of this chemical, detailing its properties and its indispensable role for researchers and procurement specialists.

Chemical Identity and Core Functionality

Designated by CAS number 112811-72-0, this quinoline derivative, with the molecular formula C14H11F2NO4 and a molecular weight of approximately 295.24 g/mol, is a key intermediate for synthesizing fluoroquinolone antibiotics, notably Moxifloxacin. Its chemical structure features a core quinoline ring system substituted with a cyclopropyl group, two fluorine atoms, and a methoxy group, all contributing to the final antibiotic's efficacy. Typically supplied as a white or off-white crystalline powder, its high purity (often ≥99%) is critical for downstream reactions.

The significance of this intermediate lies in its direct contribution to forming the active pharmaceutical ingredient (API). Pharmaceutical scientists rely on its precise chemical makeup to achieve high yields and minimal impurity formation during complex synthesis pathways.

Sourcing a High-Quality Intermediate: A Buyer's Perspective

For pharmaceutical companies and contract manufacturing organizations, securing a reliable supply of 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid is a strategic imperative. When looking to buy this compound, consider the following:

  • Manufacturer Reputation: Partner with established manufacturers who adhere to strict quality control measures. Companies in China are often competitive suppliers in this market.
  • Product Specifications: Always verify the purity (assay), physical appearance, and impurity profile against your specific requirements.
  • Technical Documentation: Request Certificates of Analysis (CoAs) and Material Safety Data Sheets (MSDS) to ensure product quality and safe handling.
  • Price Negotiation: Obtain quotes from multiple suppliers to secure competitive pricing, especially for bulk purchases.

We are a leading manufacturer and supplier of specialized pharmaceutical intermediates, including 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid. Our commitment to quality and reliable supply ensures that your pharmaceutical synthesis processes are supported by the highest standards. We encourage R&D professionals and procurement managers to contact us for a quote and explore how our high-purity intermediate can benefit your production needs.