The reliable production of essential chemical compounds is the backbone of many industries, from pharmaceuticals to diagnostics. 4-Aminohippuric Acid (CAS 61-78-9), a compound valued for its diagnostic and research applications, involves specific synthesis pathways that are critical to understand for B2B procurement. As a chemical manufacturer, we utilize optimized processes to ensure the consistent quality and availability of this vital intermediate.

Understanding the Synthesis of 4-Aminohippuric Acid

The synthesis of 4-Aminohippuric Acid typically involves a multi-step process starting with readily available precursors. A common route begins with the reaction of 4-nitrobenzoyl chloride with glycine. This step forms an amide linkage, yielding N-(4-nitrobenzoyl)glycine.

The subsequent crucial step involves the reduction of the nitro group (-NO2) to an amino group (-NH2). This is often achieved through chemical reduction methods. For instance, using reducing agents like tin (Sn) or iron (Fe) in the presence of an acid (such as hydrochloric acid, HCl) effectively converts the nitro compound to the desired amino compound. The overall reaction can be summarized as:

1. Acylation: 4-Nitrobenzoyl chloride + Glycine → N-(4-nitrobenzoyl)glycine + HCl

2. Reduction: N-(4-nitrobenzoyl)glycine + Reducing Agent → 4-Aminohippuric Acid

After synthesis, purification is a critical stage. Techniques such as recrystallization, often from water or organic solvents, are employed to achieve the high purity required for diagnostic and pharmaceutical applications. Ensuring minimal residual starting materials and by-products is key to delivering a quality product that users can trust when they buy.

Raw Material Sourcing for Manufacturers

The efficiency and cost-effectiveness of producing 4-Aminohippuric Acid (CAS 61-78-9) are heavily dependent on the reliable sourcing of raw materials. Key precursors include:

  • 4-Nitrobenzoyl Chloride: This is often synthesized from 4-nitrobenzoic acid.
  • Glycine: As the simplest amino acid, glycine is widely available.
  • Reducing Agents: Such as tin metal or iron powder.
  • Acids: Hydrochloric acid is commonly used in the reduction step.

As a dedicated manufacturer, we maintain strong relationships with reliable suppliers of these raw materials, ensuring a stable and consistent production pipeline. This vertical integration allows us to control quality from the very beginning and offer competitive prices to our clients.

Why Choose Our Manufacturing Services?

When you need to purchase high-quality 4-Aminohippuric Acid, partnering with an experienced manufacturer like us provides significant advantages. We leverage our expertise in chemical synthesis and purification to deliver a product that meets stringent purity requirements for diagnostic and pharmaceutical applications. Our commitment to quality control, efficient production, and global logistics makes us a reliable partner for all your chemical sourcing needs. Contact us today to learn more about our manufacturing capabilities and to obtain a quotation for buying 4-Aminohippuric Acid.