For procurement managers in the pharmaceutical sector, sourcing critical intermediates like 1-(2-Ethoxy-ethyl)-2-piperidin-4-yl-1H-benzimidazole (CAS 110963-63-8) is a cornerstone of efficient drug manufacturing. This compound serves as a vital building block for the widely used antihistamine, Bilastine. Ensuring a stable supply of high-quality intermediate directly impacts the cost-effectiveness and reliability of the final pharmaceutical product.

When evaluating potential manufacturers and suppliers, several factors are paramount. Firstly, the purity of the intermediate is non-negotiable. Typically, a purity of 98% or higher is required for pharmaceutical applications. This specification ensures that the subsequent synthesis steps are efficient and that the final API meets regulatory standards. Procurement managers should always request Certificates of Analysis (CoA) for each batch to verify purity and identify any potential impurities.

Secondly, supply chain reliability is crucial. Establishing a relationship with a reputable manufacturer, particularly one with a strong presence in China, can offer significant advantages in terms of competitive pricing and consistent availability. Companies that can demonstrate robust quality control processes and a track record of timely delivery are preferred. When looking to buy this intermediate, consider suppliers who can offer flexible order quantities, from grams for R&D to metric tons for large-scale production.

Furthermore, understanding the chemical properties and applications is essential. 1-(2-Ethoxy-ethyl)-2-piperidin-4-yl-1H-benzimidazole is described as a white to off-white powder, stable at room temperature, and soluble in organic solvents. Its primary use as a Bilastine intermediate means that its quality directly influences the efficacy and safety of Bilastine, a non-sedating H1-antihistamine used for allergic rhinitis and chronic idiopathic urticaria.

To effectively source this pharmaceutical intermediate, procurement professionals should leverage industry networks and online B2B platforms. Engaging with manufacturers who provide detailed product specifications, transparent pricing, and efficient customer service is key. For those looking to purchase or obtain a quote, starting with a clear inquiry detailing required quantities and purity specifications will streamline the process and help identify the best supplier for your needs.