The Crucial Role of (3R,4S)-3-Hydroxy-4-phenylazetidin-2-one in Anticancer Therapies
The relentless pursuit of effective cancer treatments places immense importance on the chemical building blocks that form the foundation of modern pharmaceuticals. Among these, (3R,4S)-3-Hydroxy-4-phenylazetidin-2-one (CAS: 132127-34-5) stands out as a particularly significant pharmaceutical intermediate. Its precise chiral structure makes it indispensable for the synthesis of highly complex and vital anticancer drugs like Paclitaxel and Docetaxel. For researchers and manufacturers alike, understanding the properties and sourcing strategies for this compound is crucial for advancing therapeutic options.
A Key Component in the Fight Against Cancer
Paclitaxel, originally derived from the Pacific yew tree, revolutionized cancer treatment by interfering with cell division. Its synthesis, often through semi-synthetic routes, relies heavily on key intermediates. (3R,4S)-3-Hydroxy-4-phenylazetidin-2-one is one such critical component, enabling the precise molecular architecture required for Paclitaxel's biological activity. Similarly, Docetaxel, a semi-synthetic analog of Paclitaxel, also utilizes this intermediate in its production. The demand for these drugs means a consistent and high-quality supply of (3R,4S)-3-Hydroxy-4-phenylazetidin-2-one is essential for global healthcare.
Specifications That Matter for Pharmaceutical Procurement
When procuring (3R,4S)-3-Hydroxy-4-phenylazetidin-2-one, key specifications include its high purity (often ≥98% by HPLC), its white solid appearance, and its specific stereochemistry. Researchers need to ensure that the intermediate's properties align with their synthesis protocols. For example, melting point data (187-188°C) and solubility information are vital for process development. Procurement managers frequently request quotes from multiple suppliers to compare pricing and availability, looking for manufacturers in China known for their stringent quality control and competitive offerings. Reliable suppliers provide comprehensive documentation, including Certificates of Analysis (COA), ensuring the material meets the required standards.
Why Partner with NINGBO INNO PHARMCHEM CO.,LTD.?
As a dedicated manufacturer and supplier of pharmaceutical intermediates, NINGBO INNO PHARMCHEM CO.,LTD. specializes in providing high-quality (3R,4S)-3-Hydroxy-4-phenylazetidin-2-one. Our commitment to excellence ensures that our products meet the rigorous demands of the pharmaceutical industry. We understand the importance of stability, purity, and timely delivery. By partnering with us, you gain access to a reliable source for this critical intermediate, backed by strong quality assurance and customer support. We offer flexible purchasing options, catering to both research quantities and bulk manufacturing needs. Let us be your trusted partner in securing this essential chemical for your cancer therapeutic production.
Exploring Future Applications and Innovation
The unique structural features of (3R,4S)-3-Hydroxy-4-phenylazetidin-2-one also make it an attractive candidate for research into novel therapeutic agents. Its ability to influence cellular processes, akin to Paclitaxel, hints at broader potential in medicinal chemistry. Researchers investigating new anticancer agents, or even compounds with antimicrobial properties, might find this chiral building block a valuable starting point. As the pharmaceutical industry continues to innovate, compounds like this will undoubtedly play a key role in the development of next-generation medicines.
For companies seeking to buy or order (3R,4S)-3-Hydroxy-4-phenylazetidin-2-one, engaging with a reputable manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. is crucial. We are committed to supporting your research and production objectives with high-quality pharmaceutical intermediates sourced reliably from China.
Perspectives & Insights
Quantum Pioneer 24
“As a dedicated manufacturer and supplier of pharmaceutical intermediates, NINGBO INNO PHARMCHEM CO.”
Bio Explorer X
“Our commitment to excellence ensures that our products meet the rigorous demands of the pharmaceutical industry.”
Nano Catalyst AI
“By partnering with us, you gain access to a reliable source for this critical intermediate, backed by strong quality assurance and customer support.”