In the intricate world of pharmaceutical manufacturing, the quality and availability of chemical intermediates are paramount. Among these vital compounds is D-4-Hydroxyphenylglycine (CAS 22818-40-2), a chiral amino acid derivative that plays a significant role in the synthesis of crucial antibiotic drugs. As a dedicated supplier of high-quality chemical raw materials, we understand the importance of this intermediate for our B2B clients in the pharmaceutical sector.

The Role of D-4-Hydroxyphenylglycine in Antibiotic Production

D-4-Hydroxyphenylglycine, often referred to as D-PHPG, is primarily recognized for its application as a side-chain precursor in the production of semi-synthetic penicillins and cephalosporins. Specifically, it is a key building block for popular antibiotics such as amoxicillin and cefadroxil. The 'D-' configuration of this phenylglycine derivative is essential for conferring the desired antibacterial spectrum and potency to these life-saving medications. For R&D scientists and production managers, ensuring a consistent supply of this specific enantiomer is critical to maintain the integrity and efficacy of the final drug product.

Beyond Amoxicillin: Diverse Pharmaceutical Applications

While its use in amoxicillin and cefadroxil synthesis is most prominent, D-4-Hydroxyphenylglycine's utility extends further within the pharmaceutical industry. Its chiral nature makes it valuable in various asymmetric synthesis routes. Furthermore, high-purity grades can serve as impurity reference standards in pharmaceutical quality control. This ensures that manufacturers can accurately identify and quantify any related substances that might arise during the complex drug manufacturing process. For companies looking to buy D-4-Hydroxyphenylglycine, its versatility as both a synthetic precursor and a quality assurance tool makes it a valuable commodity.

Sourcing Strategies: Finding the Right Manufacturer and Supplier

When procuring D-4-Hydroxyphenylglycine (CAS 22818-40-2), partnering with a reliable manufacturer is key. We, as a leading chemical supplier, focus on delivering consistent quality and dependable supply chains. Our manufacturing processes are geared towards producing this intermediate with high purity, meeting the stringent demands of pharmaceutical clients. When you consider purchasing from a Chinese manufacturer, it's important to look for partners who:

  • Provide detailed product specifications and Certificates of Analysis (CoA).
  • Offer competitive pricing for bulk orders.
  • Demonstrate robust quality management systems.
  • Have a track record of reliable delivery and customer service.

For procurement specialists, initiating an inquiry for D-4-Hydroxyphenylglycine involves specifying the required quantity and purity. Obtaining price quotations from multiple established suppliers will help in making an informed decision. The aim is to establish a long-term partnership with a supplier who understands the critical nature of pharmaceutical intermediates.

In summary, D-4-Hydroxyphenylglycine (CAS 22818-40-2) is an indispensable component in the pharmaceutical industry, particularly for antibiotic production. Its precise chemical structure and high purity are essential for synthesizing effective drugs like amoxicillin and cefadroxil. By focusing on sourcing from reputable manufacturers and suppliers, pharmaceutical companies can secure the quality raw materials needed to produce life-saving treatments.