For professionals in the chemical and pharmaceutical sectors, identifying and securing reliable sources of key intermediates is fundamental to successful production and research. Diethyl Acetamidomalonate (DEAM), bearing CAS number 1068-90-2, is one such critical compound, recognized for its indispensable role in the synthesis of various vitamins and pharmaceuticals.

The chemical structure of Diethyl Acetamidomalonate makes it an exceptionally versatile building block for organic synthesis. Its primary utility lies in its ability to serve as a precursor for creating complex molecules. Notably, DEAM is instrumental in the synthesis pathways for essential vitamins such as Vitamin B1 (Thiamine) and Vitamin B6 (Pyridoxine). These vitamins are vital for human health, and their industrial production relies heavily on efficient and pure intermediate compounds like DEAM.

Beyond its role in vitamin production, Diethyl Acetamidomalonate is also a significant intermediate in the pharmaceutical industry. Its application is seen in the synthesis of various drugs, including barbiturates and non-steroidal anti-inflammatory agents. More critically, it is a key precursor in the synthesis of Fingolimod, a vital medication used to manage multiple sclerosis. The demand for such advanced pharmaceuticals directly translates to a consistent need for high-quality DEAM.

For companies looking to purchase Diethyl Acetamidomalonate, understanding product specifications is crucial. A high assay, typically ≥99.0%, ensures the purity required for sensitive pharmaceutical syntheses. The physical appearance, often described as a white to yellow or pink crystalline powder, and its solubility characteristics are also important considerations for process integration. When sourcing this compound, particularly from international markets like China, it is essential to partner with reputable manufacturers who can guarantee consistent quality and volume.

Procurement managers and R&D scientists seeking to buy Diethyl Acetamidomalonate should prioritize suppliers who offer competitive pricing for bulk orders and have robust quality control systems in place. Ensuring a stable supply chain for such a vital intermediate is key to uninterrupted production schedules and the successful development of new therapeutic agents. Engaging with established manufacturers provides the assurance of quality and reliability needed in the demanding pharmaceutical sector.