The world of chemical synthesis is constantly seeking precise and versatile building blocks to create complex molecules. (R)-(+)-3-Butyn-2-ol, identified by its CAS number 42969-65-3, is one such compound that has gained significant importance, especially within the pharmaceutical and fine chemical industries. Known also as (2R)-but-3-yn-2-ol or (R)-(+)-3-Butyn-2-ol, this chiral alcohol is a colorless transparent liquid, valued for its unique chemical properties and its role as an intermediate for crucial drug syntheses.

At its core, (R)-(+)-3-Butyn-2-ol is a chiral alcohol with a terminal alkyne group. This combination imparts it with specific reactivity patterns that are highly desirable in organic synthesis. The molecule's defined stereochemistry, indicated by the (R) configuration, is particularly critical for applications in stereoselective synthesis, a field that demands absolute precision to produce enantiomerically pure compounds. This purity is non-negotiable when these compounds are destined for pharmaceutical applications, where even slight variations can significantly impact efficacy and safety.

A prime example of its utility is its role as a precursor in the synthesis of Vorapaxar Sulfate, a medication used to prevent thrombotic events. The synthesis pathways for such complex pharmaceuticals often involve multiple steps, and the reliable supply of high-quality intermediates like (R)-(+)-3-Butyn-2-ol is essential. Sourcing this compound from experienced suppliers in China ensures that the stringent purity standards of ≥98.0% are met, facilitating smooth and successful drug manufacturing processes.

The physical characteristics of (R)-(+)-3-Butyn-2-ol, such as its boiling point of 108-111 ºC and a flash point of 10 ºC, inform its handling and storage requirements. It must be kept in cool, well-ventilated areas, away from ignition sources. Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. provide detailed specifications and safety guidelines to ensure the compound is used responsibly. The demand for this versatile chiral building block continues to grow as research and development in medicinal chemistry progresses, making it a key component in the supply chain for innovative therapies.

For any company engaged in advanced organic synthesis or pharmaceutical intermediate production, securing a dependable source for (R)-(+)-3-Butyn-2-ol is a strategic imperative. The expertise of Chinese chemical manufacturers in producing such specialty chemicals ensures that global industries have access to these vital materials, driving forward advancements in healthcare and beyond.