In the intricate landscape of pharmaceutical manufacturing, the quality and precision of starting materials are paramount. Among these critical compounds, (R)-(+)-3-Butyn-2-ol, identified by its CAS number 42969-65-3, stands out as an indispensable chiral intermediate. Also known by synonyms such as (2R)-but-3-yn-2-ol or (R)-(+)-3-Butyn-2-ol, this colorless transparent liquid is a cornerstone for complex organic synthesis, particularly within the pharmaceutical sector.

The significance of (R)-(+)-3-Butyn-2-ol lies in its unique molecular structure, featuring both an alkyne and a secondary alcohol group, along with a defined chiral center. This combination of features makes it a highly sought-after building block for constructing intricate molecular architectures required for advanced therapeutics. Its molecular formula is C4H6O, with a molecular weight of 70.090, and it is typically supplied with an assay of ≥98.0%, ensuring the high purity demanded by pharmaceutical applications.

One of the most prominent applications of (R)-(+)-3-Butyn-2-ol is its role as a key intermediate in the synthesis of Vorapaxar Sulfate (CAS: 705260-08-8). Vorapaxar Sulfate is a critical pharmaceutical compound known for its anticoagulant properties, used in preventing blood clots. The precise stereochemistry of (R)-(+)-3-Butyn-2-ol is crucial for ensuring the stereospecific reactions necessary for the efficient and accurate synthesis of Vorapaxar Sulfate. This demand underscores the importance of reliable (R)-(+)-3-Butyn-2-ol manufacturers and suppliers in China, who play a vital role in supporting the global pharmaceutical industry.

Beyond its primary use in Vorapaxar Sulfate synthesis, the versatile reactivity of (R)-(+)-3-Butyn-2-ol allows it to be employed in various other organic transformations. Its acetylenic structure makes it amenable to numerous reactions, positioning it as a valuable precursor for a range of fine chemicals. Industries that rely on such intermediates deeply value the consistency and purity offered by reputable suppliers. For those looking to buy (R)-(+)-3-Butyn-2-ol, partnering with experienced manufacturers in China provides access to both quality products and competitive pricing.

The physical and chemical properties of (R)-(+)-3-Butyn-2-ol, including its density of 0.89 g/cm³ and a boiling point between 108-111 ºC, contribute to its suitability for controlled manufacturing processes. Its flash point of 10 ºC indicates the need for careful handling due to flammability, necessitating storage in cool, ventilated areas. NINGBO INNO PHARMCHEM CO.,LTD., as a prominent supplier in China, ensures that these compounds are produced and packaged with the utmost attention to safety and quality standards. By understanding the specific requirements of chiral synthesis, manufacturers can provide the reliable materials that drive innovation in drug development.