Ethyl 6-bromoimidazo[1,2-a]pyridine-3-carboxylate (CAS 372198-69-1) is a complex organic molecule that plays a crucial role in various fields of chemical synthesis, particularly in medicinal chemistry. Its unique structure and reactive sites make it a valuable intermediate for developing novel pharmaceuticals, including agents with antimycobacterial properties and inhibitors targeting key cellular pathways.

NINGBO INNO PHARMCHEM CO.,LTD., a prominent B2B chemical manufacturer and supplier in China, offers this compound with a focus on high purity and consistent quality. Understanding its synthesis and applications is key for researchers and procurement specialists seeking reliable sourcing solutions.

Synthetic Routes and Quality Assurance

The synthesis of Ethyl 6-bromoimidazo[1,2-a]pyridine-3-carboxylate typically involves multi-step chemical reactions. Common approaches begin with bromination of an imidazo[1,2-a]pyridine precursor, followed by esterification. For instance, reacting 2-amino-5-bromopyridine with N,N-dimethylformamide dimethyl acetal, followed by cyclization with ethyl bromoacetate in the presence of a base like sodium bicarbonate, are established methods. At NINGBO INNO PHARMCHEM, we adhere to optimized synthesis protocols to ensure a product purity of ≥98.20% (HPLC), validated through rigorous quality control measures.

Key Applications in Research and Development

The primary utility of Ethyl 6-bromoimidazo[1,2-a]pyridine-3-carboxylate lies in its role as a versatile building block. Its derivatives have demonstrated significant potential in:

  • Antimycobacterial Agents: This intermediate is crucial for synthesizing compounds that exhibit efficacy against Mycobacterium tuberculosis, addressing a global health challenge.
  • PI3K Inhibitors: It serves as a precursor for developing inhibitors of the PI3K pathway, which is integral to cell signaling and often dysregulated in cancers and other diseases.
  • Drug Discovery: Its heterocyclic nature allows for extensive structural modification, enabling the creation of diverse libraries of novel compounds for screening in various therapeutic areas.

Why Partner with NINGBO INNO PHARMCHEM?

As a leading chemical supplier from China, we provide distinct advantages: competitive pricing, guaranteed high purity, and a stable supply chain. We cater to both research-scale and bulk industrial needs, ensuring that our clients have uninterrupted access to this vital intermediate. Our team is dedicated to providing exceptional customer service and technical support, assisting you with product inquiries and purchase decisions.

Purchase Ethyl 6-bromoimidazo[1,2-a]pyridine-3-carboxylate Today

For procurement managers and research scientists seeking a dependable source for Ethyl 6-bromoimidazo[1,2-a]pyridine-3-carboxylate, look no further. Contact NINGBO INNO PHARMCHEM CO.,LTD. to discuss your needs, request a quotation, and learn more about how our high-quality intermediates can advance your pharmaceutical development projects. Buy with confidence from a trusted Chinese manufacturer.