Fmoc-Glu-OtBu (84793-07-7) in Peptide Synthesis: A Buyer's Guide
The intricate process of peptide synthesis relies on a consistent supply of high-quality protected amino acid derivatives. Among these, Fmoc-Glu-OtBu, designated by CAS number 84793-07-7, is a critical reagent for introducing glutamic acid residues into peptide chains. For procurement managers and R&D scientists, understanding the nuances of sourcing this compound is key to successful and cost-effective peptide manufacturing.
Key Specifications for Fmoc-Glu-OtBu Procurement
When you intend to buy Fmoc-Glu-OtBu, several critical specifications must be met. The compound's chemical identity is Nα-Fmoc-L-glutamic acid α-tert-butyl ester, with a molecular formula of C24H27NO6 and a molecular weight of 425.47. The most important quality parameter is purity, typically specified as 98% by HPLC. This high level of purity ensures that the Fmoc-Glu-OtBu will participate efficiently in coupling reactions without introducing unwanted by-products that could complicate downstream purification or compromise the final peptide’s integrity.
Packaging is another crucial consideration. Fmoc-Glu-OtBu is usually supplied in solid form, and it is typically available in research-friendly quantities such as 1g, 5g, and 25g. For larger scale operations, inquire about bulk packaging options. The long-term storage recommendations, usually cool and dry conditions, are also important for maintaining product stability.
Finding Reliable Suppliers and Competitive Pricing
Identifying reliable suppliers for Fmoc-Glu-OtBu involves more than just comparing prices. While competitive pricing is essential, especially when looking to buy in bulk, it should not overshadow the importance of quality and consistency. Reputable manufacturers and suppliers will readily provide a Certificate of Analysis (CoA) for each batch, detailing its purity, physical properties, and analytical data. This documentation is indispensable for quality assurance in pharmaceutical and research settings.
When searching for a supplier, consider those with a strong presence in the market and positive customer feedback. Companies specializing in amino acid derivatives and peptide synthesis reagents are often the best choice. It is advisable to reach out to multiple suppliers, such as NINGBO INNO PHARMCHEM CO.,LTD., to compare quotes and discuss your specific needs. Clarify lead times, shipping options, and any technical support available. By carefully evaluating these factors, you can ensure you buy high-quality Fmoc-Glu-OtBu that meets your project’s requirements efficiently and economically.
Perspectives & Insights
Nano Explorer 01
“The compound's chemical identity is Nα-Fmoc-L-glutamic acid α-tert-butyl ester, with a molecular formula of C24H27NO6 and a molecular weight of 425.”
Data Catalyst One
“The most important quality parameter is purity, typically specified as 98% by HPLC.”
Chem Thinker Labs
“This high level of purity ensures that the Fmoc-Glu-OtBu will participate efficiently in coupling reactions without introducing unwanted by-products that could complicate downstream purification or compromise the final peptide’s integrity.”