The creation of peptide libraries is a cornerstone of modern drug discovery, enabling high-throughput screening for new therapeutic leads. Within these combinatorial efforts, specific amino acid derivatives play crucial roles. Fmoc-Lys(Boc)-OH is one such vital reagent, providing a protected lysine building block that is essential for generating diverse peptide sequences. For researchers and procurement specialists, understanding its utility and how to source it effectively is key. As a leading supplier and manufacturer, we aim to illuminate its importance.

Fmoc-Lys(Boc)-OH, identified by CAS number 71989-26-9, is a cornerstone in Solid-Phase Peptide Synthesis (SPPS), the primary method for constructing peptide libraries. The compound features the Fmoc group for alpha-amino protection and the Boc group for side-chain protection of lysine. This dual protection allows for sequential coupling of amino acids, with the Fmoc group being removed under basic conditions, and the Boc group being selectively cleaved by acid, typically during the final resin cleavage step. This orthogonality is critical when building complex libraries where each amino acid must be precisely introduced.

When constructing peptide libraries, diversity is key, and lysine's side chain offers a valuable point for modification or branching. Fmoc-Lys(Boc)-OH allows chemists to precisely incorporate lysine residues, and subsequently, the protected epsilon-amino group can be utilized for further conjugation, such as attaching labels, creating branched peptides, or forming cyclic structures. This flexibility makes it an indispensable tool for researchers looking to explore a wide chemical space. For those needing to buy this reagent, ensuring high purity is paramount, as even minor impurities can lead to a significant number of inactive or aberrant sequences in a large library.

Securing a reliable supply of high-purity Fmoc-Lys(Boc)-OH is essential for the success of peptide library synthesis projects. We, as a committed manufacturer in China, focus on delivering products that meet rigorous quality standards. This includes providing detailed analytical data, such as HPLC and NMR, to confirm purity. Procurement managers should prioritize working with suppliers who offer consistent quality and have the capacity to fulfill orders for the large quantities often required for library synthesis. The price for such materials is always a consideration, and sourcing from a direct supplier can often yield cost efficiencies.

The ability to reliably purchase Fmoc-Lys(Boc)-OH with guaranteed purity is fundamental to accelerating drug discovery pipelines. Whether you are synthesizing a focused library or a large-scale combinatorial set, our high-quality Fmoc-Lys(Boc)-OH is designed to meet your demanding requirements. We invite research institutions and pharmaceutical companies to explore our offerings and request a quote for their peptide library synthesis needs. Partnering with a trusted chemical supplier ensures your research is built on a solid foundation.